Homeostatic and injury‐induced microglia behavior in the aging brain

Summary Microglia cells are essential for brain homeostasis and have essential roles in neurodegenerative diseases. Aging is the main risk factor for most neurodegenerative diseases, and age‐related changes in microglia may contribute to the susceptibility of the aging brain to dysfunction and neuro...

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Veröffentlicht in:	Aging cell 2014-02, Vol.13 (1), p.60-69
Hauptverfasser:	Hefendehl, Jasmin K., Neher, Jonas J., Sühs, Rafael B., Kohsaka, Shinichi, Skodras, Angelos, Jucker, Mathias
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - pathology Analysis Animals Behavior Brain Brain - pathology Brain Injuries - pathology Cell Movement Cell Shape Homeostasis Imaging, Three-Dimensional in vivo imaging Lasers Mice Mice, Inbred C57BL microglia Microglia - pathology neocortex Nervous system diseases Neurodegeneration Original Physiological aspects Rodents Surveys
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