Moderate alcohol induces stress proteins HSF1 and hsp70 and inhibits pro-inflammatory cytokines resulting in endotoxin tolerance1, 2

Binge or moderate alcohol exposure impairs host defense and increases susceptibility to infection due to compromised innate immune responses. However there is a lack of consensus on the molecular mechanism by which alcohol mediates this immunosuppression. Here, we show that cellular stress proteins...

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Veröffentlicht in:	The Journal of immunology (1950) 2014-07, Vol.193 (4), p.1975-1987
Hauptverfasser:	Muralidharan, Sujatha, Ambade, Aditya, Fulham, Melissa A., Deshpande, Janhavee, Catalano, Donna, Mandrekar, Pranoti
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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