Epigenetic targets for novel therapies of lung diseases

In spite of substantial advances in defining the immunobiology and function of structural cells in lung diseases there is still insufficient knowledge to develop fundamentally new classes of drugs to treat many lung diseases. For example, there is a compelling need for new therapeutic approaches to...

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Veröffentlicht in:	Pharmacology & therapeutics (Oxford) 2015-03, Vol.147, p.91-110
Hauptverfasser:	Comer, Brian S, Ba, Mariam, Singer, Cherie A, Gerthoffer, William T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bronchodilator Agents - administration & dosage DNA Methylation - drug effects DNA Methylation - genetics Drug Delivery Systems - methods Drug Delivery Systems - trends Epigenesis, Genetic - drug effects Epigenesis, Genetic - genetics Gene Targeting - methods Gene Targeting - trends Humans Lung Diseases - genetics Lung Diseases - therapy
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