BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells

Several components of the Wnt signaling cascade have been shown to function either as tumor suppressor proteins or as oncogenes in multiple human cancers, underscoring the relevance of this pathway in oncogenesis and the need for further investigation of Wnt signaling components as potential targets...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2009-10, Vol.69 (19), p.7577-7586
Hauptverfasser:	MANI, Mala, CARRASCO, Daniel E, MYEROFF, Lois L, MARKOWITZ, Sanford D, ANDERSON, Kenneth C, CARRASCO, Daniel R, YUNYU ZHANG, TAKADA, Kohichi, GATT, Moshe E, DUTTA-SIMMONS, Jui, IKEDA, Hiroshi, DIAZ-GRIFFERO, Felipe, PENA-CRUZ, Victor, BERTAGNOLLI, Monica
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Cell Growth Processes - physiology Cell Line, Tumor Cell Movement - physiology Colonic Neoplasms - blood supply Colonic Neoplasms - genetics Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Disease Progression Humans Hyaluronan Receptors - biosynthesis Hyaluronan Receptors - genetics Medical sciences Multiple Myeloma - blood supply Multiple Myeloma - genetics Multiple Myeloma - metabolism Multiple Myeloma - pathology Neoplasm Metastasis Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Neovascularization, Pathologic - genetics Neovascularization, Pathologic - metabolism Neovascularization, Pathologic - pathology Pharmacology. Drug treatments RNA, Messenger - genetics RNA, Messenger - metabolism Tumors Vascular Endothelial Growth Factor A - biosynthesis Vascular Endothelial Growth Factor A - genetics Wnt Proteins - metabolism
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