Survey of commercial Rhodiola products revealed species diversity and potential safety issues
The adulteration of herbal products is a threat to consumer safety. Here we surveyed the species composition of commercial Rhodiola products using DNA barcoding as a supervisory method. A Rhodiola dietary supplement DNA barcode database was successfully constructed using 82 voucher samples from 10 R...
Gespeichert in:
| Veröffentlicht in: | Scientific reports 2015-02, Vol.5 (1), p.8337-8337, Article 8337 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 8337 |
|---|---|
| container_issue | 1 |
| container_start_page | 8337 |
| container_title | Scientific reports |
| container_volume | 5 |
| creator | Xin, Tianyi Li, Xiaojin Yao, Hui Lin, Yulin Ma, Xiaochong Cheng, Ruiyang Song, Jingyuan Ni, Lianghong Fan, Congzhao Chen, Shilin |
| description | The adulteration of herbal products is a threat to consumer safety. Here we surveyed the species composition of commercial
Rhodiola
products using DNA barcoding as a supervisory method. A
Rhodiola
dietary supplement DNA barcode database was successfully constructed using 82 voucher samples from 10
Rhodiola
species. Based on the DNA barcoding standard operating procedure (SOP), we used this database to identify 100 Rhodiolae Crenulatae Radix et Rhizoma decoction piece samples that were purchased from drug stores and hospitals. The results showed that only 36 decoction piece sequences (40%) were authentic
R. crenulata
, which is recorded in Chinese Pharmacopeia, whereas the other samples were all adulterants and may indicate a potential safety issue. Among the adulterants, 35 sequences (38.9%) were authenticated as
R. serrata
, nine sequences (10%) were authenticated as
R. rosea
, which is documented in the United States Pharmacopeia and the remaining samples were authenticated as other three
Rhodiola
species. This result indicates decoction pieces that are available in the market have complex origins and DNA barcoding is a convenient tool for market supervision. |
| doi_str_mv | 10.1038/srep08337 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4321177</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1653128628</sourcerecordid><originalsourceid>FETCH-LOGICAL-c504t-8499039bbabe6fb55562d98741826586298388d7a8762e55248b16ca8046b1993</originalsourceid><addsrcrecordid>eNplkV1L5DAYRoO4qLhe7B-QgDcqjOajSZMbQQa_QFhYdy-XkKZvNdI2NWkH5t8bGR1GzU1CcvLkhAehX5ScUcLVeYowEMV5uYX2GCnEjHHGtjfWu-ggpWeSh2C6oHoH7TIhJSVE76H_D1NcwBKHBrvQdRCdty3-8xRqH1qLhxjqyY0JR1iAbaHGaQDnIeHaLyAmPy6x7Ws8hBH68e1qsg3kTZ_SBOkn-tHYNsHB-7yP_l1f_Z3fzu5_39zNL-9nTpBinKlCa8J1VdkKZFMJISSrtSoLqpgUSjKtuFJ1aVUpGQjBClVR6awihayo1nwfXaxyh6nqoHbZJdrWDNF3Ni5NsN58Pun9k3kMC1NwRmlZ5oDj94AYXrL4aDqfHLSt7SFMyVApOGXZRGX06Av6HKbY5-8ZqrRiRK6MTlaUiyHlipq1DCXmrTez7i2zh5v2a_KjpQycroCUj_pHiBtPfkt7BYdxogM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1898206199</pqid></control><display><type>article</type><title>Survey of commercial Rhodiola products revealed species diversity and potential safety issues</title><source>MEDLINE</source><source>Nature Free</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Springer Nature OA Free Journals</source><creator>Xin, Tianyi ; Li, Xiaojin ; Yao, Hui ; Lin, Yulin ; Ma, Xiaochong ; Cheng, Ruiyang ; Song, Jingyuan ; Ni, Lianghong ; Fan, Congzhao ; Chen, Shilin</creator><creatorcontrib>Xin, Tianyi ; Li, Xiaojin ; Yao, Hui ; Lin, Yulin ; Ma, Xiaochong ; Cheng, Ruiyang ; Song, Jingyuan ; Ni, Lianghong ; Fan, Congzhao ; Chen, Shilin</creatorcontrib><description>The adulteration of herbal products is a threat to consumer safety. Here we surveyed the species composition of commercial
Rhodiola
products using DNA barcoding as a supervisory method. A
Rhodiola
dietary supplement DNA barcode database was successfully constructed using 82 voucher samples from 10
Rhodiola
species. Based on the DNA barcoding standard operating procedure (SOP), we used this database to identify 100 Rhodiolae Crenulatae Radix et Rhizoma decoction piece samples that were purchased from drug stores and hospitals. The results showed that only 36 decoction piece sequences (40%) were authentic
R. crenulata
, which is recorded in Chinese Pharmacopeia, whereas the other samples were all adulterants and may indicate a potential safety issue. Among the adulterants, 35 sequences (38.9%) were authenticated as
R. serrata
, nine sequences (10%) were authenticated as
R. rosea
, which is documented in the United States Pharmacopeia and the remaining samples were authenticated as other three
Rhodiola
species. This result indicates decoction pieces that are available in the market have complex origins and DNA barcoding is a convenient tool for market supervision.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/srep08337</identifier><identifier>PMID: 25661009</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>45 ; 45/22 ; 45/23 ; 45/29 ; 45/77 ; 631/154/1438 ; 631/158/670 ; 631/449 ; 692/700/155 ; Deoxyribonucleic acid ; DNA ; DNA Barcoding, Taxonomic ; DNA, Plant - analysis ; DNA, Plant - genetics ; Drugs, Chinese Herbal - analysis ; Humanities and Social Sciences ; multidisciplinary ; Rhodiola - genetics ; Safety ; Science ; Species composition ; Species diversity</subject><ispartof>Scientific reports, 2015-02, Vol.5 (1), p.8337-8337, Article 8337</ispartof><rights>The Author(s) 2015</rights><rights>Copyright Nature Publishing Group Feb 2015</rights><rights>Copyright © 2015, Macmillan Publishers Limited. All rights reserved 2015 Macmillan Publishers Limited. All rights reserved</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c504t-8499039bbabe6fb55562d98741826586298388d7a8762e55248b16ca8046b1993</citedby><cites>FETCH-LOGICAL-c504t-8499039bbabe6fb55562d98741826586298388d7a8762e55248b16ca8046b1993</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321177/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321177/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,41096,42165,51551,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25661009$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xin, Tianyi</creatorcontrib><creatorcontrib>Li, Xiaojin</creatorcontrib><creatorcontrib>Yao, Hui</creatorcontrib><creatorcontrib>Lin, Yulin</creatorcontrib><creatorcontrib>Ma, Xiaochong</creatorcontrib><creatorcontrib>Cheng, Ruiyang</creatorcontrib><creatorcontrib>Song, Jingyuan</creatorcontrib><creatorcontrib>Ni, Lianghong</creatorcontrib><creatorcontrib>Fan, Congzhao</creatorcontrib><creatorcontrib>Chen, Shilin</creatorcontrib><title>Survey of commercial Rhodiola products revealed species diversity and potential safety issues</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>The adulteration of herbal products is a threat to consumer safety. Here we surveyed the species composition of commercial
Rhodiola
products using DNA barcoding as a supervisory method. A
Rhodiola
dietary supplement DNA barcode database was successfully constructed using 82 voucher samples from 10
Rhodiola
species. Based on the DNA barcoding standard operating procedure (SOP), we used this database to identify 100 Rhodiolae Crenulatae Radix et Rhizoma decoction piece samples that were purchased from drug stores and hospitals. The results showed that only 36 decoction piece sequences (40%) were authentic
R. crenulata
, which is recorded in Chinese Pharmacopeia, whereas the other samples were all adulterants and may indicate a potential safety issue. Among the adulterants, 35 sequences (38.9%) were authenticated as
R. serrata
, nine sequences (10%) were authenticated as
R. rosea
, which is documented in the United States Pharmacopeia and the remaining samples were authenticated as other three
Rhodiola
species. This result indicates decoction pieces that are available in the market have complex origins and DNA barcoding is a convenient tool for market supervision.</description><subject>45</subject><subject>45/22</subject><subject>45/23</subject><subject>45/29</subject><subject>45/77</subject><subject>631/154/1438</subject><subject>631/158/670</subject><subject>631/449</subject><subject>692/700/155</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA Barcoding, Taxonomic</subject><subject>DNA, Plant - analysis</subject><subject>DNA, Plant - genetics</subject><subject>Drugs, Chinese Herbal - analysis</subject><subject>Humanities and Social Sciences</subject><subject>multidisciplinary</subject><subject>Rhodiola - genetics</subject><subject>Safety</subject><subject>Science</subject><subject>Species composition</subject><subject>Species diversity</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNplkV1L5DAYRoO4qLhe7B-QgDcqjOajSZMbQQa_QFhYdy-XkKZvNdI2NWkH5t8bGR1GzU1CcvLkhAehX5ScUcLVeYowEMV5uYX2GCnEjHHGtjfWu-ggpWeSh2C6oHoH7TIhJSVE76H_D1NcwBKHBrvQdRCdty3-8xRqH1qLhxjqyY0JR1iAbaHGaQDnIeHaLyAmPy6x7Ws8hBH68e1qsg3kTZ_SBOkn-tHYNsHB-7yP_l1f_Z3fzu5_39zNL-9nTpBinKlCa8J1VdkKZFMJISSrtSoLqpgUSjKtuFJ1aVUpGQjBClVR6awihayo1nwfXaxyh6nqoHbZJdrWDNF3Ni5NsN58Pun9k3kMC1NwRmlZ5oDj94AYXrL4aDqfHLSt7SFMyVApOGXZRGX06Av6HKbY5-8ZqrRiRK6MTlaUiyHlipq1DCXmrTez7i2zh5v2a_KjpQycroCUj_pHiBtPfkt7BYdxogM</recordid><startdate>20150209</startdate><enddate>20150209</enddate><creator>Xin, Tianyi</creator><creator>Li, Xiaojin</creator><creator>Yao, Hui</creator><creator>Lin, Yulin</creator><creator>Ma, Xiaochong</creator><creator>Cheng, Ruiyang</creator><creator>Song, Jingyuan</creator><creator>Ni, Lianghong</creator><creator>Fan, Congzhao</creator><creator>Chen, Shilin</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150209</creationdate><title>Survey of commercial Rhodiola products revealed species diversity and potential safety issues</title><author>Xin, Tianyi ; Li, Xiaojin ; Yao, Hui ; Lin, Yulin ; Ma, Xiaochong ; Cheng, Ruiyang ; Song, Jingyuan ; Ni, Lianghong ; Fan, Congzhao ; Chen, Shilin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c504t-8499039bbabe6fb55562d98741826586298388d7a8762e55248b16ca8046b1993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>45</topic><topic>45/22</topic><topic>45/23</topic><topic>45/29</topic><topic>45/77</topic><topic>631/154/1438</topic><topic>631/158/670</topic><topic>631/449</topic><topic>692/700/155</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA Barcoding, Taxonomic</topic><topic>DNA, Plant - analysis</topic><topic>DNA, Plant - genetics</topic><topic>Drugs, Chinese Herbal - analysis</topic><topic>Humanities and Social Sciences</topic><topic>multidisciplinary</topic><topic>Rhodiola - genetics</topic><topic>Safety</topic><topic>Science</topic><topic>Species composition</topic><topic>Species diversity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xin, Tianyi</creatorcontrib><creatorcontrib>Li, Xiaojin</creatorcontrib><creatorcontrib>Yao, Hui</creatorcontrib><creatorcontrib>Lin, Yulin</creatorcontrib><creatorcontrib>Ma, Xiaochong</creatorcontrib><creatorcontrib>Cheng, Ruiyang</creatorcontrib><creatorcontrib>Song, Jingyuan</creatorcontrib><creatorcontrib>Ni, Lianghong</creatorcontrib><creatorcontrib>Fan, Congzhao</creatorcontrib><creatorcontrib>Chen, Shilin</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xin, Tianyi</au><au>Li, Xiaojin</au><au>Yao, Hui</au><au>Lin, Yulin</au><au>Ma, Xiaochong</au><au>Cheng, Ruiyang</au><au>Song, Jingyuan</au><au>Ni, Lianghong</au><au>Fan, Congzhao</au><au>Chen, Shilin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Survey of commercial Rhodiola products revealed species diversity and potential safety issues</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2015-02-09</date><risdate>2015</risdate><volume>5</volume><issue>1</issue><spage>8337</spage><epage>8337</epage><pages>8337-8337</pages><artnum>8337</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>The adulteration of herbal products is a threat to consumer safety. Here we surveyed the species composition of commercial
Rhodiola
products using DNA barcoding as a supervisory method. A
Rhodiola
dietary supplement DNA barcode database was successfully constructed using 82 voucher samples from 10
Rhodiola
species. Based on the DNA barcoding standard operating procedure (SOP), we used this database to identify 100 Rhodiolae Crenulatae Radix et Rhizoma decoction piece samples that were purchased from drug stores and hospitals. The results showed that only 36 decoction piece sequences (40%) were authentic
R. crenulata
, which is recorded in Chinese Pharmacopeia, whereas the other samples were all adulterants and may indicate a potential safety issue. Among the adulterants, 35 sequences (38.9%) were authenticated as
R. serrata
, nine sequences (10%) were authenticated as
R. rosea
, which is documented in the United States Pharmacopeia and the remaining samples were authenticated as other three
Rhodiola
species. This result indicates decoction pieces that are available in the market have complex origins and DNA barcoding is a convenient tool for market supervision.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>25661009</pmid><doi>10.1038/srep08337</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2045-2322 |
| ispartof | Scientific reports, 2015-02, Vol.5 (1), p.8337-8337, Article 8337 |
| issn | 2045-2322 2045-2322 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4321177 |
| source | MEDLINE; Nature Free; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Springer Nature OA Free Journals |
| subjects | 45 45/22 45/23 45/29 45/77 631/154/1438 631/158/670 631/449 692/700/155 Deoxyribonucleic acid DNA DNA Barcoding, Taxonomic DNA, Plant - analysis DNA, Plant - genetics Drugs, Chinese Herbal - analysis Humanities and Social Sciences multidisciplinary Rhodiola - genetics Safety Science Species composition Species diversity |
| title | Survey of commercial Rhodiola products revealed species diversity and potential safety issues |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T08%3A47%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Survey%20of%20commercial%20Rhodiola%20products%20revealed%20species%20diversity%20and%20potential%20safety%20issues&rft.jtitle=Scientific%20reports&rft.au=Xin,%20Tianyi&rft.date=2015-02-09&rft.volume=5&rft.issue=1&rft.spage=8337&rft.epage=8337&rft.pages=8337-8337&rft.artnum=8337&rft.issn=2045-2322&rft.eissn=2045-2322&rft_id=info:doi/10.1038/srep08337&rft_dat=%3Cproquest_pubme%3E1653128628%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1898206199&rft_id=info:pmid/25661009&rfr_iscdi=true |