The CENP-A N-Tail Confers Epigenetic Stability to Centromeres via the CENP-T Branch of the CCAN in Fission Yeast

In most eukaryotes, centromeres are defined epigenetically by presence of the histone H3 variant CENP-A [1–3]. CENP-A-containing chromatin recruits the constitutive centromere-associated network (CCAN) of proteins, which in turn directs assembly of the outer kinetochore to form microtubule attachmen...

Ausführliche Beschreibung