H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

In differentiated cells, aging is associated with hypermethylation of DNA regions enriched in repressive histone post-translational modifications. However, the chromatin marks associated with changes in DNA methylation in adult stem cells during lifetime are still largely unknown. Here, DNA methylat...

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Veröffentlicht in:	Genome research 2015-01, Vol.25 (1), p.27-40
Hauptverfasser:	Fernández, Agustín F, Bayón, Gustavo F, Urdinguio, Rocío G, Toraño, Estela G, García, María G, Carella, Antonella, Petrus-Reurer, Sandra, Ferrero, Cecilia, Martinez-Camblor, Pablo, Cubillo, Isabel, García-Castro, Javier, Delgado-Calle, Jesús, Pérez-Campo, Flor M, Riancho, José A, Bueno, Clara, Menéndez, Pablo, Mentink, Anouk, Mareschi, Katia, Claire, Fabian, Fagnani, Corrado, Medda, Emanuela, Toccaceli, Virgilia, Brescianini, Sonia, Moran, Sebastián, Esteller, Manel, Stolzing, Alexandra, de Boer, Jan, Nisticò, Lorenza, Stazi, Maria A, Fraga, Mario F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Aged Aged, 80 and over Aging - genetics Cell Differentiation Cells, Cultured Child Child, Preschool Chromatin - genetics DNA - genetics DNA Methylation Epigenesis, Genetic Histones - genetics Humans Microarray Analysis Middle Aged Promoter Regions, Genetic Protein Processing, Post-Translational Sequence Analysis, DNA Stem Cells - cytology Twins, Monozygotic Young Adult
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