Gemfibrozil attenuates the inflammatory response and protects rats from abdominal sepsis

Sepsis is a serious condition characterized by an infectious process that induces a severe systemic inflammatory response. In this study, the effects of gemfibrozil (GFZ) on the inflammatory response associated with abdominal sepsis were investigated using a rat model of cecal-ligation and puncture...

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Veröffentlicht in:	Experimental and therapeutic medicine 2015-03, Vol.9 (3), p.1018-1022
Hauptverfasser:	CÁMARA-LEMARROY, CARLOS R, GUZMAN-DE LA GARZA, FRANCISCO J, CORDERO-PEREZ, PAULA, IBARRA-HERNANDEZ, JUAN M, MUÑOZ-ESPINOSA, LINDA E, FERNANDEZ-GARZA, NANCY E
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Cell cycle Cytokines Dehydrogenases Dosage and administration Drug dosages Fatty acids fibrates Gemfibrozil Inflammation Ischemia Laboratory animals Lipid peroxidation Lipids Mortality Oxidative stress Permeability Prevention Proteins rat Rodents Sepsis Smooth muscle Standard deviation Studies Values Variance analysis
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