Oocyte Spindle Proteomics Analysis Leading to Rescue of Chromosome Congression Defects in Cloned Embryos

Embryos produced by somatic cell nuclear transfer (SCNT) display low term developmental potential. This is associated with deficiencies in spindle composition prior to activation and at early mitotic divisions, including failure to assemble certain proteins on the spindle. The protein-deficient spin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of proteome research 2010-11, Vol.9 (11), p.6025-6032
Hauptverfasser:	Han, Zhiming, Liang, Cheng-Guang, Cheng, Yong, Duan, Xunbao, Zhong, Zhisheng, Potireddy, Santhi, Moncada, Camilo, Merali, Salim, Latham, Keith E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aurora Kinase B Aurora Kinases Casein Kinase I - deficiency Chromosome Segregation - drug effects Chromosome Segregation - genetics Clathrin Heavy Chains - analysis Clathrin Heavy Chains - drug effects Cloning, Organism Dynactin Complex Embryo, Mammalian Mice Mice, Inbred Strains Microtubule-Associated Proteins - deficiency Oocytes - chemistry Oocytes - ultrastructure Protein-Serine-Threonine Kinases - deficiency Proteins - analysis Proteomics - methods RNA, Messenger - administration & dosage RNA, Messenger - therapeutic use Spindle Apparatus - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!