Glutamine is highly effective in preventing in vivo cobalt-induced oxidative stress in rat liver

AIM: To evaluate the in vivo effect of glutamine on cobaltgenerated oxidative stress and (HO-1)induction in rat liver. METHODS: Fasted female Wistar rats received a single injection of cobalt chloride (375 μmol/kg body weight) and then were killed at different times. Lipid peroxidation and soluble a...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2005-06, Vol.11 (23), p.3533-3538
Hauptverfasser:	Gonzales, Soledad, Polizio, Ariel-H, Erario, María-A, Tomaro, María-L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Research Catalase - metabolism Cobalt - antagonists & inhibitors Cobalt - toxicity Female Glutamine - pharmacology Glutathione - metabolism Glutathione Peroxidase - metabolism Liver - drug effects Liver - metabolism Oxidative Stress - drug effects Rats Rats, Wistar Superoxide Dismutase - metabolism 动物实验氧化损伤肝损伤药物预防谷氨酸盐
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