Simvastatin mitigates functional and structural impairment of lung and right ventricle in a rat model of cigarette smoke-induced COPD

This study is conducted to investigate an effect of simvastatin on cigarette smoke-induced COPD. Rats were exposed to air (control) and cigarette smoke (smoking) in presence and absence of simvastatin. Heart and lung tissues were harvested for histopathologic and morphometric analysis. Body weight o...

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Veröffentlicht in:International journal of clinical and experimental pathology 2014-01, Vol.7 (12), p.8553-8562
Hauptverfasser: Wang, Yajie, Jiang, Xue, Zhang, Lihai, Wang, Lihong, Li, Zhu, Sun, Wuzhuang
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Sprache:eng
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