Tenosynovitis caused by a novel nontuberculous Mycobacterium species initially misidentified as a member of the Mycobacterium tuberculosis complex

We present a case of tenosynovitis caused by a novel, slowly growing, nonchromogenic, nontuberculous mycobacterium (NTM). Originally misidentified as Mycobacterium tuberculosis complex, the NTM cross-reacts with the M. tuberculosis complex nucleic acid hybridization probe, a M. tuberculosis gamma in...

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Veröffentlicht in:	Journal of clinical microbiology 2014-12, Vol.52 (12), p.4414-4418
Hauptverfasser:	Simner, Patricia J, Hyle, Emily P, Buckwalter, Seanne P, Branda, John A, Brown-Elliott, Barbara A, Franklin, Jameelah, Toney, Nadege C, de Man, Tom J B, Wallace, Jr, Richard J, Vasireddy, Ravikiran, Gandhi, Rajesh T, Wengenack, Nancy L
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Case Reports Cluster Analysis Diagnostic Errors Diagnostic Tests, Routine DNA, Bacterial - chemistry DNA, Bacterial - genetics DNA, Ribosomal - chemistry DNA, Ribosomal - genetics Female Humans Interferon-gamma Release Tests Middle Aged Molecular Sequence Data Mycobacterium Infections, Nontuberculous - diagnosis Mycobacterium Infections, Nontuberculous - microbiology Mycobacterium Infections, Nontuberculous - pathology Mycobacterium tuberculosis Nontuberculous Mycobacteria - classification Nontuberculous Mycobacteria - genetics Nontuberculous Mycobacteria - isolation & purification Nucleic Acid Hybridization Phylogeny RNA, Ribosomal, 16S - genetics Sequence Analysis, DNA Tenosynovitis - diagnosis Tenosynovitis - microbiology Tenosynovitis - pathology
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Zusammenfassung:	We present a case of tenosynovitis caused by a novel, slowly growing, nonchromogenic, nontuberculous mycobacterium (NTM). Originally misidentified as Mycobacterium tuberculosis complex, the NTM cross-reacts with the M. tuberculosis complex nucleic acid hybridization probe, a M. tuberculosis gamma interferon release assay, and is closely related to M. tuberculosis by 16S rRNA gene sequencing.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.00967-14