The effect of HAART-induced HIV suppression on circulating markers of inflammation and immune activation

OBJECTIVES:To investigate the impact of HAART-induced HIV suppression on levels of 24 serological biomarkers of inflammation and immune activation. DESIGN:A prospective cohort study. METHODS:Biomarkers were measured with multiplex assays in centralized laboratories using stored serum samples contrib...

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Veröffentlicht in:	AIDS (London) 2015-02, Vol.29 (4), p.463-471
Hauptverfasser:	Wada, Nikolas Itaru, Jacobson, Lisa P, Margolick, Joseph B, Breen, Elizabeth Crabb, Macatangay, Bernard, Penugonda, Sudhir, Martínez-Maza, Otoniel, Bream, Jay H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Antiretroviral Therapy, Highly Active Biomarkers - blood C-Reactive Protein - drug effects CD4 Lymphocyte Count Chemokines, CC - drug effects Female HIV Infections - drug therapy HIV Infections - immunology HIV-1 - drug effects HIV-1 - immunology Humans Inflammation - drug therapy Inflammation - immunology Interleukin-6 Lentivirus Lymphocyte Activation - drug effects Lymphocyte Activation - immunology Male Prospective Studies Retroviridae Treatment Outcome Tumor Necrosis Factor-alpha - drug effects
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