The Epidemiology and Outcomes of Percutaneous Coronary Intervention Before High‐Risk Noncardiac Surgery in Contemporary Practice: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) Registry

Background Percutaneous coronary intervention (PCI) is sometimes performed with the intent to lower cardiovascular risk before high‐risk noncardiac surgery (HRNCS). There are limited data on the frequency and outcome of PCIs performed in this setting. Methods and Results We assessed the frequency, c...

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Veröffentlicht in:Journal of the American Heart Association 2014-05, Vol.3 (3), p.e000388-n/a
Hauptverfasser: Muthappan, Palaniappan, Smith, Dean, Aronow, Herbert D., Eagle, Kim, Wohns, David, Fox, James, Share, David, Gurm, Hitinder S.
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container_issue 3
container_start_page e000388
container_title Journal of the American Heart Association
container_volume 3
creator Muthappan, Palaniappan
Smith, Dean
Aronow, Herbert D.
Eagle, Kim
Wohns, David
Fox, James
Share, David
Gurm, Hitinder S.
description Background Percutaneous coronary intervention (PCI) is sometimes performed with the intent to lower cardiovascular risk before high‐risk noncardiac surgery (HRNCS). There are limited data on the frequency and outcome of PCIs performed in this setting. Methods and Results We assessed the frequency, characteristics, and in‐hospital outcomes of patients undergoing PCI as part of the preoperative workup for HRNCS among all 61 145 elective PCIs performed between 2002 and 2009 at 14 hospitals in the Blue Cross Blue Shield of Michigan Cardiovascular Consortium. Propensity matching was performed to compare outcomes of patients undergoing PCI before HRNCS with all other elective PCI patients. The frequency of PCI before HRNCS was low (4.2%). Patients undergoing PCI before HRNCS were older (67.3 versus 64.9 years, P
doi_str_mv 10.1161/JAHA.113.000388
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There are limited data on the frequency and outcome of PCIs performed in this setting. Methods and Results We assessed the frequency, characteristics, and in‐hospital outcomes of patients undergoing PCI as part of the preoperative workup for HRNCS among all 61 145 elective PCIs performed between 2002 and 2009 at 14 hospitals in the Blue Cross Blue Shield of Michigan Cardiovascular Consortium. Propensity matching was performed to compare outcomes of patients undergoing PCI before HRNCS with all other elective PCI patients. The frequency of PCI before HRNCS was low (4.2%). Patients undergoing PCI before HRNCS were older (67.3 versus 64.9 years, P&lt;0.0001) and had a greater burden of comorbidity. Patients undergoing PCI before HRNCS had an increase in unadjusted major adverse cardiovascular events, postprocedure transfusion, contrast‐induced nephropathy, nephropathy requiring dialysis, and same‐admission coronary artery bypass graft surgery, but there was no difference in mortality (0.27% versus 0.14%, P=0.11). However, in propensity score–matched samples, there was a significant difference only in nephropathy requiring dialysis. Conclusions The incidence of PCI performed in preparation for high‐risk noncardiac surgery is low, and these procedures are currently being performed on a highly selected high‐risk patient population.</description><identifier>ISSN: 2047-9980</identifier><identifier>EISSN: 2047-9980</identifier><identifier>DOI: 10.1161/JAHA.113.000388</identifier><identifier>PMID: 24820654</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Aged ; angioplasty ; Blue Cross Blue Shield Insurance Plans - statistics &amp; numerical data ; Cardiovascular Diseases - surgery ; epidemiology ; Female ; Humans ; Male ; Michigan - epidemiology ; Middle Aged ; Original Research ; Outcome and Process Assessment (Health Care) ; Percutaneous Coronary Intervention - statistics &amp; numerical data ; Practice Patterns, Physicians' - statistics &amp; numerical data ; Preoperative Care - adverse effects ; Preoperative Care - methods ; preoperative revascularization ; Registries ; Risk Reduction Behavior ; stents ; Surgical Procedures, Operative - adverse effects ; Surgical Procedures, Operative - methods ; Treatment Outcome</subject><ispartof>Journal of the American Heart Association, 2014-05, Vol.3 (3), p.e000388-n/a</ispartof><rights>2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.</rights><rights>2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4384-85a495cbbedb559378de97a8d927e7e9360a3d9adbbbb3df53d06fc5d464f6ec3</citedby><cites>FETCH-LOGICAL-c4384-85a495cbbedb559378de97a8d927e7e9360a3d9adbbbb3df53d06fc5d464f6ec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309038/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309038/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,11541,27901,27902,46027,46451,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24820654$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Muthappan, Palaniappan</creatorcontrib><creatorcontrib>Smith, Dean</creatorcontrib><creatorcontrib>Aronow, Herbert D.</creatorcontrib><creatorcontrib>Eagle, Kim</creatorcontrib><creatorcontrib>Wohns, David</creatorcontrib><creatorcontrib>Fox, James</creatorcontrib><creatorcontrib>Share, David</creatorcontrib><creatorcontrib>Gurm, Hitinder S.</creatorcontrib><title>The Epidemiology and Outcomes of Percutaneous Coronary Intervention Before High‐Risk Noncardiac Surgery in Contemporary Practice: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) Registry</title><title>Journal of the American Heart Association</title><addtitle>J Am Heart Assoc</addtitle><description>Background Percutaneous coronary intervention (PCI) is sometimes performed with the intent to lower cardiovascular risk before high‐risk noncardiac surgery (HRNCS). There are limited data on the frequency and outcome of PCIs performed in this setting. Methods and Results We assessed the frequency, characteristics, and in‐hospital outcomes of patients undergoing PCI as part of the preoperative workup for HRNCS among all 61 145 elective PCIs performed between 2002 and 2009 at 14 hospitals in the Blue Cross Blue Shield of Michigan Cardiovascular Consortium. Propensity matching was performed to compare outcomes of patients undergoing PCI before HRNCS with all other elective PCI patients. The frequency of PCI before HRNCS was low (4.2%). Patients undergoing PCI before HRNCS were older (67.3 versus 64.9 years, P&lt;0.0001) and had a greater burden of comorbidity. Patients undergoing PCI before HRNCS had an increase in unadjusted major adverse cardiovascular events, postprocedure transfusion, contrast‐induced nephropathy, nephropathy requiring dialysis, and same‐admission coronary artery bypass graft surgery, but there was no difference in mortality (0.27% versus 0.14%, P=0.11). However, in propensity score–matched samples, there was a significant difference only in nephropathy requiring dialysis. Conclusions The incidence of PCI performed in preparation for high‐risk noncardiac surgery is low, and these procedures are currently being performed on a highly selected high‐risk patient population.</description><subject>Aged</subject><subject>angioplasty</subject><subject>Blue Cross Blue Shield Insurance Plans - statistics &amp; numerical data</subject><subject>Cardiovascular Diseases - surgery</subject><subject>epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Michigan - epidemiology</subject><subject>Middle Aged</subject><subject>Original Research</subject><subject>Outcome and Process Assessment (Health Care)</subject><subject>Percutaneous Coronary Intervention - statistics &amp; numerical data</subject><subject>Practice Patterns, Physicians' - statistics &amp; numerical data</subject><subject>Preoperative Care - adverse effects</subject><subject>Preoperative Care - methods</subject><subject>preoperative revascularization</subject><subject>Registries</subject><subject>Risk Reduction Behavior</subject><subject>stents</subject><subject>Surgical Procedures, Operative - adverse effects</subject><subject>Surgical Procedures, Operative - methods</subject><subject>Treatment Outcome</subject><issn>2047-9980</issn><issn>2047-9980</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><recordid>eNqFksFO3DAURaOqVUHAurvKS7oYcGI7ibuoNBNBBwQFAV1Hjv2SuE3iqe1MNbt-Qr-RL6mjUERX9cYv8r3HN88vit7F-CSO0_j0crlehoqcYIxJnr-K9hNMswXnOX79ot6Ljpz7FjQ4TTLC-NtoL6F5glNG96PHhxbQ2UYr6LXpTLNDYlDoZvTS9OCQqdEtWDl6MYAZHSqMNYOwO3QxeLBbGLw2A1pBbSygtW7ax1-_77T7jr6YQQqrtJDofrQNBIsegj3Y-o2xE-LWCum1hI8B5oLVO3RuTY98SLTqRkCFNc7N5X2roVNTnGstW92IwJrwZiucHDthJ7Qz1uuxR8er6yL5gO6g0c7b3WH0phadg6On_SD6en72UKwXVzefL4rl1UJSktNFzgTlTFYVqIoxTrJcAc9ErniSQQacpFgQxYWqwiKqZkThtJZM0ZTWKUhyEH2auZux6kHJ0BwrunJjdR9-tzRCl_-eDLotG7MtKcE8PGAAHD8BrPkxgvNlr52ErpubX8YsoYQSlsVBejpL5dQjC_XzNTEup-Eop-EIFSnn4QiO9y_TPev_jkIQ0FnwU3ew-x9v-iYspPkDbb3L6A</recordid><startdate>20140512</startdate><enddate>20140512</enddate><creator>Muthappan, Palaniappan</creator><creator>Smith, Dean</creator><creator>Aronow, Herbert D.</creator><creator>Eagle, Kim</creator><creator>Wohns, David</creator><creator>Fox, James</creator><creator>Share, David</creator><creator>Gurm, Hitinder S.</creator><general>Blackwell Publishing Ltd</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140512</creationdate><title>The Epidemiology and Outcomes of Percutaneous Coronary Intervention Before High‐Risk Noncardiac Surgery in Contemporary Practice: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) Registry</title><author>Muthappan, Palaniappan ; Smith, Dean ; Aronow, Herbert D. ; Eagle, Kim ; Wohns, David ; Fox, James ; Share, David ; Gurm, Hitinder S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4384-85a495cbbedb559378de97a8d927e7e9360a3d9adbbbb3df53d06fc5d464f6ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>angioplasty</topic><topic>Blue Cross Blue Shield Insurance Plans - statistics &amp; numerical data</topic><topic>Cardiovascular Diseases - surgery</topic><topic>epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Michigan - epidemiology</topic><topic>Middle Aged</topic><topic>Original Research</topic><topic>Outcome and Process Assessment (Health Care)</topic><topic>Percutaneous Coronary Intervention - statistics &amp; numerical data</topic><topic>Practice Patterns, Physicians' - statistics &amp; numerical data</topic><topic>Preoperative Care - adverse effects</topic><topic>Preoperative Care - methods</topic><topic>preoperative revascularization</topic><topic>Registries</topic><topic>Risk Reduction Behavior</topic><topic>stents</topic><topic>Surgical Procedures, Operative - adverse effects</topic><topic>Surgical Procedures, Operative - methods</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Muthappan, Palaniappan</creatorcontrib><creatorcontrib>Smith, Dean</creatorcontrib><creatorcontrib>Aronow, Herbert D.</creatorcontrib><creatorcontrib>Eagle, Kim</creatorcontrib><creatorcontrib>Wohns, David</creatorcontrib><creatorcontrib>Fox, James</creatorcontrib><creatorcontrib>Share, David</creatorcontrib><creatorcontrib>Gurm, Hitinder S.</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of the American Heart Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Muthappan, Palaniappan</au><au>Smith, Dean</au><au>Aronow, Herbert D.</au><au>Eagle, Kim</au><au>Wohns, David</au><au>Fox, James</au><au>Share, David</au><au>Gurm, Hitinder S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Epidemiology and Outcomes of Percutaneous Coronary Intervention Before High‐Risk Noncardiac Surgery in Contemporary Practice: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) Registry</atitle><jtitle>Journal of the American Heart Association</jtitle><addtitle>J Am Heart Assoc</addtitle><date>2014-05-12</date><risdate>2014</risdate><volume>3</volume><issue>3</issue><spage>e000388</spage><epage>n/a</epage><pages>e000388-n/a</pages><issn>2047-9980</issn><eissn>2047-9980</eissn><abstract>Background Percutaneous coronary intervention (PCI) is sometimes performed with the intent to lower cardiovascular risk before high‐risk noncardiac surgery (HRNCS). There are limited data on the frequency and outcome of PCIs performed in this setting. Methods and Results We assessed the frequency, characteristics, and in‐hospital outcomes of patients undergoing PCI as part of the preoperative workup for HRNCS among all 61 145 elective PCIs performed between 2002 and 2009 at 14 hospitals in the Blue Cross Blue Shield of Michigan Cardiovascular Consortium. Propensity matching was performed to compare outcomes of patients undergoing PCI before HRNCS with all other elective PCI patients. The frequency of PCI before HRNCS was low (4.2%). Patients undergoing PCI before HRNCS were older (67.3 versus 64.9 years, P&lt;0.0001) and had a greater burden of comorbidity. Patients undergoing PCI before HRNCS had an increase in unadjusted major adverse cardiovascular events, postprocedure transfusion, contrast‐induced nephropathy, nephropathy requiring dialysis, and same‐admission coronary artery bypass graft surgery, but there was no difference in mortality (0.27% versus 0.14%, P=0.11). However, in propensity score–matched samples, there was a significant difference only in nephropathy requiring dialysis. Conclusions The incidence of PCI performed in preparation for high‐risk noncardiac surgery is low, and these procedures are currently being performed on a highly selected high‐risk patient population.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>24820654</pmid><doi>10.1161/JAHA.113.000388</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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subjects Aged
angioplasty
Blue Cross Blue Shield Insurance Plans - statistics & numerical data
Cardiovascular Diseases - surgery
epidemiology
Female
Humans
Male
Michigan - epidemiology
Middle Aged
Original Research
Outcome and Process Assessment (Health Care)
Percutaneous Coronary Intervention - statistics & numerical data
Practice Patterns, Physicians' - statistics & numerical data
Preoperative Care - adverse effects
Preoperative Care - methods
preoperative revascularization
Registries
Risk Reduction Behavior
stents
Surgical Procedures, Operative - adverse effects
Surgical Procedures, Operative - methods
Treatment Outcome
title The Epidemiology and Outcomes of Percutaneous Coronary Intervention Before High‐Risk Noncardiac Surgery in Contemporary Practice: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) Registry
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