Effect of Hypericum perforatum L. Extract on Insulin Resistance and Lipid Metabolic Disorder in High‐Fat‐Diet Induced Obese Mice

Natural product Hypericum perforatum L. has been used in folk medicine to improve mental performance. However, the effect of H. perforatum L. on metabolism is still unknown. In order to test whether H. perforatum L. extract (EHP) has an effect on metabolic syndrome, we treated diet induced obese (DI...

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Veröffentlicht in:	Phytotherapy research 2015-01, Vol.29 (1), p.86-92
Hauptverfasser:	Tian, Jin‐ying, Tao, Rong‐ya, Zhang, Xiao‐lin, Liu, Qian, He, Yi‐bo, Su, Ya‐lun, Ji, Teng‐fei, Ye, Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	animal disease models Animals catalytic activity Diet, High-Fat - adverse effects dyslipidemia fatty acids Fatty Acids - metabolism genes glucose Glucose - metabolism glucose clamp technique Glucose Tolerance Test glucose tolerance tests high fat diet high performance liquid chromatography Humans Hypericum - chemistry Hypericum perforatum Hypericum perforatum L Insulin Resistance insulin tolerance test lipid metabolism Lipid Metabolism - drug effects Male messenger RNA metabolic diseases metabolic syndrome Metabolic Syndrome - drug therapy Metabolic Syndrome - metabolism Mice Mice, Inbred C57BL Mice, Obese Muscle, Skeletal - metabolism obesity Obesity - drug therapy Obesity - metabolism oxidation phytotherapy Plant Components, Aerial - chemistry Plant Extracts - pharmacology Protein Tyrosine Phosphatase, Non-Receptor Type 1 protein-tyrosine-phosphatase PTP1B inhibitor Recombinant Proteins - metabolism skeletal muscle spectroscopy thin layer chromatography traditional medicine
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