A novel role for ezrin in breast cancer angio/lymphangiogenesis

Recent evidence suggests that tumour lymphangiogenesis promotes lymph node metastasis, a major prognostic factor for survival of breast cancer patients. However, signaling mechanisms involved in tumour-induced lymphangiogenesis remain poorly understood. The expression of ezrin, a membrane cytoskelet...

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Veröffentlicht in:	Breast cancer research : BCR 2014-09, Vol.16 (5), p.438-438, Article 438
Hauptverfasser:	Ghaffari, Abdi, Hoskin, Victoria, Szeto, Alvin, Hum, Maaike, Liaghati, Navid, Nakatsu, Kanji, LeBrun, David, Madarnas, Yolanda, Sengupta, Sandip, Elliott, Bruce E
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Breast cancer Breast Neoplasms - blood supply Breast Neoplasms - metabolism Breast Neoplasms - pathology Cytoskeletal Proteins - physiology Development and progression Female Humans Interleukin-6 - metabolism Lymphangiogenesis Metastasis Mice, Inbred CBA Mice, Knockout Mutation, Missense Neoplasm Invasiveness Neoplasm Transplantation Neovascularization, Pathologic - metabolism Phosphorylation Physiological aspects Prognosis Protein Processing, Post-Translational Rats, Sprague-Dawley src-Family Kinases STAT3 Transcription Factor - metabolism Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor C - metabolism
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