Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling

The NF-κB family of transcription factors regulates numerous cellular processes, including cell proliferation and survival responses. The constitutive activation of NF-κB has also emerged as an important oncogenic driver in many malignancies, such as activated B-cell like diffuse large B cell lympho...

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Veröffentlicht in:Experimental cell research 2015-02, Vol.331 (1), p.58-72
Hauptverfasser: Jackson, Shawn S., Oberley, Christopher, Hooper, Christopher P., Grindle, Kreg, Wuerzberger-Davis, Shelly, Wolff, Jared, McCool, Kevin, Rui, Lixin, Miyamoto, Shigeki
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Sprache:eng
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