Protein carbonylation and heat shock proteins in human skeletal muscle: relationships to age and sarcopenia

Aging is associated with a gradual loss of muscle mass termed sarcopenia, which has significant impact on quality-of-life. Because oxidative stress is proposed to negatively impact upon musculoskeletal aging, we investigated links between human aging and markers of oxidative stress, and relationship...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2015-02, Vol.70 (2), p.174-181
Hauptverfasser:	Beltran Valls, Maria R, Wilkinson, Daniel J, Narici, Marco V, Smith, Kenneth, Phillips, Bethan E, Caporossi, Daniela, Atherton, Philip J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Aging - physiology alpha-Crystallin B Chain - metabolism Carbon monoxide Chemical reactions Heat shock proteins HSP27 Heat-Shock Proteins - metabolism HSP70 Heat-Shock Proteins - metabolism Humans Male Mitochondria, Muscle Muscle Strength - physiology Muscle, Skeletal - metabolism Musculoskeletal system Original Oxidative stress Protein Carbonylation - physiology Proteins Sarcopenia - metabolism Sarcopenia - physiopathology
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