Multigeneration Reproduction and Male Developmental Toxicity Studies on Atrazine in Rats

BACKGROUND Reproductive toxicity of Atrazine (ATR) was evaluated in two rat multigenerational studies. Development of male reproductive parameters was evaluated in separate studies after prenatal or postnatal exposure. METHODS In multigenerational studies, rats received dietary concentrations of 0,...

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Veröffentlicht in:	Birth defects research. Part B. Developmental and reproductive toxicology 2014-06, Vol.101 (3), p.237-253
Hauptverfasser:	DeSesso, John M., Scialli, Anthony R., White, Tacey E. K., Breckenridge, Charles B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals atrazine Atrazine - administration & dosage Atrazine - toxicity Body Weight Dose-Response Relationship, Drug Endpoint Determination Epididymis - drug effects Epididymis - metabolism Female gestation Lactation Male male development Maternal Exposure multigeneration reproduction No-Observed-Adverse-Effect Level Organ Size - drug effects postcoitum Pregnancy rat Rats Reproduction - drug effects Reproductive system Rodents Sperm Spermatozoa - drug effects Studies Testosterone Testosterone - blood Toxicity
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