Hyaluronic acid stimulates neovascularization during the regeneration of bone marrow after ablation

Restoration of vasculature is a critical component for successful integration of implants in musculoskeletal tissue. Sodium hyaluronate (NaHY) has been used as a carrier for demineralized bone matrix (DBM). DBM is osteoinductive and osteoconductive, but whether NaHY by itself has an effect is not kn...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2011-03, Vol.96A (3), p.575-583
Hauptverfasser:	Raines, Andrew L., Sunwoo, MoonHae, Gertzman, Arthur A., Thacker, Kipling, Guldberg, Robert E., Schwartz, Zvi, Boyan, Barbara D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Techniques Animals Biological and medical sciences Bone Marrow - diagnostic imaging Bone Marrow - drug effects Bone Marrow - surgery Bone Matrix - drug effects Bone Matrix - metabolism Bone Regeneration - drug effects Contrast media. Radiopharmaceuticals DBM plus hyaluronic acid Feasibility Studies histomorphometry Hyaluronic Acid - pharmacology Male Medical sciences microCT using a contrast agent to label vasculature Neovascularization, Physiologic - drug effects Pharmacology. Drug treatments rat tibial bone marrow ablation Rats Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments Tibia - blood supply Tibia - drug effects Tibia - pathology Time Factors vasculogenesis X-Ray Microtomography
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