(4‐[6‐(4‐isopropoxyphenyl)pyrazolo [1,5‐a]pyrimidin‐3‐yl] quinoline) is a novel inhibitor of autophagy

Background and Purpose Autophagy is an important intracellular degradation system, which is related to various diseases. In preliminary experiments we found that D4‐[6‐(4‐isopropoxyphenyl)pyrazolo [1,5‐a]pyrimidin‐3‐yl] quinoline (DMH1) inhibited autophagy responses. However DMH1 also inhibits the s...

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Veröffentlicht in:British journal of pharmacology 2014-11, Vol.171 (21), p.4970-4980
Hauptverfasser: Sheng, Yue, Sun, Bo, Guo, Wen‐Ting, Liu, Xiao, Wang, Yu‐Chun, Xie, Xin, Xiao, Xiao‐Lin, Li, Na, Dong, De‐Li
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Sprache:eng
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