Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC

Binding of the chromatin remodeling complex NoRC to RNA complementary to the rDNA promoter mediates transcriptional repression. TIP5, the largest subunit of NoRC, is involved in recruitment to rDNA by interactions with promoter-bound TTF-I, pRNA, and acetylation of H4K16. TIP5 domains that recognize...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Structure (London) 2015-01, Vol.23 (1), p.80-92
Hauptverfasser:	Tallant, Cynthia, Valentini, Erica, Fedorov, Oleg, Overvoorde, Lois, Ferguson, Fleur M., Filippakopoulos, Panagis, Svergun, Dmitri I., Knapp, Stefan, Ciulli, Alessio
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Chromatin Assembly and Disassembly Chromosomal Proteins, Non-Histone - chemistry Chromosomal Proteins, Non-Histone - metabolism Histones - chemistry Histones - metabolism Humans Models, Molecular Molecular Sequence Data Protein Binding Protein Interaction Domains and Motifs Protein Structure, Quaternary Sequence Homology, Amino Acid Zinc Fingers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!