Antiproliferative effect of the jararhagin toxin on B16F10 murine melanoma

Malignant melanoma is a less common but highly dangerous form of skin cancer; it starts in the melanocytes cells found in the outer layer of the skin. Jararhagin toxin, a metalloproteinase isolated from Bothrops jararaca snake venom acts upon several biological processes, as inflammation, pain, plat...

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Veröffentlicht in:	BMC complementary and alternative medicine 2014-11, Vol.14 (1), p.446-446, Article 446
Hauptverfasser:	Maria, Durvanei Augusto, da Silva, Manuela Garcia Laveli, Correia Junior, Mario Cesar, Ruiz, Itamar Romano Garcia
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquisitions & mergers Analysis Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Apoptosis Apoptosis - drug effects Biological products industry Bothrops Bothrops jararaca Bothrops jararaca Venom Care and treatment Caspase 3 - metabolism Cell adhesion & migration Cell Adhesion - drug effects Cell Cycle - drug effects Cell division Cell Line, Tumor Cell Proliferation - drug effects Crotalid Venoms - isolation & purification Crotalid Venoms - pharmacology Crotalid Venoms - therapeutic use Diagnosis Gene expression Laboratories Medical equipment and supplies industry Medical test kit industry Melanoma Melanoma - drug therapy Melanoma - metabolism Melanoma, Cutaneous Malignant Metalloendopeptidases - isolation & purification Metalloendopeptidases - pharmacology Metalloendopeptidases - therapeutic use Metalloproteases - pharmacology Metalloproteases - therapeutic use Metastasis Mice Platelet Aggregation Platelet Aggregation Inhibitors - pharmacology Platelet Aggregation Inhibitors - therapeutic use Risk factors Skin Neoplasms - drug therapy Skin Neoplasms - metabolism Snakes Toxins Venom
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