Paired tumor biopsy analysis and safety data from a pilot study evaluating Tremelimumab - a monoclonal antibody against CTLA-4 - in combination with ablative therapy in patients with hepatocellular carcinoma (HCC)

BackgroundTremelimumab is a fully human monoclonal antibody that binds to CTLA-4 expressed on the surface of activated T lymphocytes and results in inhibition of B7-CTLA-4-mediated down regulation of T cell activation. Both transcatheter arterial chemoembolization (TACE) and radiofrequency ablation...

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Veröffentlicht in:	Journal for immunotherapy of cancer 2014-11, Vol.2 (S3), p.P98-P98, Article P98
Hauptverfasser:	Duffy, Austin, Kerkar, Sid P, Kleiner, David E, Ulahannan, Susanna, Kurtoglu, Metin, Rusher, Oxana, Fioravanti, Suzanne, Walker, Melissa, Figg, William D, Compton, Kathryn, Venkatesan, Aradhana, Abi-Jaoudeh, Nadine, Wood, Brad, Greten, Tim F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Immunotherapy Liver cancer Liver cirrhosis Poster Presentation
Online-Zugang:	Volltext
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