Transcriptional regulation of IFN-λ genes in Hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-κB complex

Hepatitis C virus (HCV) infection in hepatocytes stimulates innate antiviral responses including the production of type III interferons (IFN-λ), including IL-28A, IL-28B, and IL-29 (Figure 1). However, the molecular mechanism(s) regulating the expression of IFN- λ genes in HCV-infected hepatocytes r...

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Veröffentlicht in:Journal for immunotherapy of cancer 2014-11, Vol.2 (S3), p.P173-P173, Article P173
Hauptverfasser: Lee, Hai-Chon, Youn, Je-In, Lee, Kyungwha, Yong, Hwanyul, Seong, Seung-Yong
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Sprache:eng
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