Targeted TLR9-activation/STAT3-blocking abrogates immunosuppressive functions of myeloid-derived suppressor cells from late-stage prostate cancer patients

Recent clinical advances underscored that elimination of tumor-induced immunosuppression is prerequisite for successful therapy of advanced human cancers. The myeloid-derived suppressor cells (MDSCs) are one of the major populations limiting T cell-mediated antitumor immune responses in late-stage s...

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Veröffentlicht in:	Journal for immunotherapy of cancer 2014-11, Vol.2 (Suppl 3), p.P104-P104
Hauptverfasser:	Md Sakib Hossain, Dewan, Moreira, Dayson, Zhang, Qifang, Forman, Stephen J, Pal, Sumanta, Kortylewski, Marcin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer research Immunotherapy Metastasis Poster Presentation Prostate cancer Tumors
Online-Zugang:	Volltext
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