Regulation of Early Cartilage Destruction in Inflammatory Arthritis by Death Receptor 3

Objective To investigate the role of death receptor 3 (DR‐3) and its ligand tumor necrosis factor–like molecule 1A (TL1A) in the early stages of inflammatory arthritis. Methods Antigen‐induced arthritis (AIA) was generated in C57BL/6 mice deficient in the DR‐3 gene (DR3−/−) and their DR3+/+ (wild‐ty...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2014-10, Vol.66 (10), p.2762-2772
Hauptverfasser:	Wang, Eddie C. Y., Newton, Zarabeth, Hayward, Olivia A., Clark, Stephen R., Collins, Fraser, Perks, William V., Singh, Ravinder K., Twohig, Jason P., Williams, Anwen S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis Arthritis, Experimental - metabolism Arthritis, Rheumatoid - metabolism Arthritis, Rheumatoid - pathology Cartilage, Articular - metabolism Cartilage, Articular - pathology Chemokine CXCL1 - metabolism Experimental Arthritis Fibroblasts - metabolism Humans Mice Mice, Knockout Monocytes - metabolism Neutrophils Receptors, Tumor Necrosis Factor, Member 25 - metabolism Rodents Synovial Membrane - metabolism Tumor Necrosis Factor Ligand Superfamily Member 15 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!