TAS2R bitter taste receptors regulate thyroid function

Dysregulation of thyroid hormones triiodothyronine and thyroxine (T3/T4) can impact metabolism, body composition, and development. Thus, it is critical to identify novel mechanisms that impact T3/T4 production. We found that type 2 taste receptors (TAS2Rs), which are activated by bitter‐tasting comp...

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Veröffentlicht in:	The FASEB journal 2015-01, Vol.29 (1), p.164-172
Hauptverfasser:	Clark, Adam A., Dotson, Cedrick D., Elson, Amanda E. T., Voigt, Anja, Boehm, Ulrich, Meyerhof, Wolfgang, Steinle, Nanette I., Munger, Steven D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Calcium - metabolism Cell Line Female G protein‐coupled receptor Gene Expression Humans Immunohistochemistry iodide Ligands Male Mice Mice, Transgenic Middle Aged Polymorphism, Single Nucleotide Receptors, G-Protein-Coupled - agonists Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Research Communication T2R thyrocyte Thyroid Gland - cytology Thyroid Gland - metabolism Thyroid Hormones - metabolism Thyrotropin - metabolism thyroxine Tissue Distribution
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