Germline Mutations of Inhibins in Early-Onset Ovarian Epithelial Tumors

ABSTRACT To identify novel genetic bases of early‐onset epithelial ovarian tumors, we used the trio exome sequencing strategy in a patient without familial history of cancer who presented metastatic serous ovarian adenocarcinomas at 21 years of age. We identified a single de novo mutation (c.1157A&g...

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