ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study

Abstract Objective Mild traumatic brain injury (mTBI) patients are frequently admitted to high levels of care despite limited evidence suggesting benefit. Such decisions may contribute to the significant cost of caring for mTBI patients. Understanding the factors that drive disposition decision maki...

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Veröffentlicht in:The American journal of emergency medicine 2014-08, Vol.32 (8), p.844-850
Hauptverfasser: Ratcliff, Jonathan J., MD, MPH, Adeoye, Opeolu, MD, MS, Lindsell, Christopher J., PhD, Hart, Kimberly W., MA, Pancioli, Arthur, MD, McMullan, Jason T., MD, Yue, John K., BS, Nishijima, Daniel K., MD, Gordon, Wayne A., PhD, Valadka, Alex B., MD, Okonkwo, David O., MD, PhD, Lingsma, Hester F., PhD, Maas, Andrew I.R., MD, PhD, Manley, Geoffrey T., MD PhD
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container_end_page 850
container_issue 8
container_start_page 844
container_title The American journal of emergency medicine
container_volume 32
creator Ratcliff, Jonathan J., MD, MPH
Adeoye, Opeolu, MD, MS
Lindsell, Christopher J., PhD
Hart, Kimberly W., MA
Pancioli, Arthur, MD
McMullan, Jason T., MD
Yue, John K., BS
Nishijima, Daniel K., MD
Gordon, Wayne A., PhD
Valadka, Alex B., MD
Okonkwo, David O., MD, PhD
Lingsma, Hester F., PhD
Maas, Andrew I.R., MD, PhD
Manley, Geoffrey T., MD PhD
description Abstract Objective Mild traumatic brain injury (mTBI) patients are frequently admitted to high levels of care despite limited evidence suggesting benefit. Such decisions may contribute to the significant cost of caring for mTBI patients. Understanding the factors that drive disposition decision making and how disposition is associated with outcomes is necessary for developing an evidence-base supporting disposition decisions. We evaluated factors associated with emergency department triage of mTBI patients to 1 of 3 levels of care: home, inpatient floor, or intensive care unit (ICU). Methods This multicenter, prospective, cohort study included patients with isolated head trauma, a cranial computed tomography as part of routine care, and a Glasgow Coma Scale (GCS) score of 13 to 15. Data analysis was performed using multinomial logistic regression. Results Of the 304 patients included, 167 (55%) were discharged home, 76 (25%) were admitted to the inpatient floor, and 61 (20%) were admitted to the ICU. In the multivariable model, admission to the ICU, compared with floor admission, varied by study site, odds ratio (OR) 0.18 (95% confidence interval [CI], 0.06-0.57); antiplatelet/anticoagulation therapy, OR 7.46 (95% CI, 1.79-31.13); skull fracture, OR 7.60 (95% CI, 2.44-23.73); and lower GCS, OR 2.36 (95% CI, 1.05-5.30). No difference in outcome was observed between the 3 levels of care. Conclusion Clinical characteristics and local practice patterns contribute to mTBI disposition decisions. Level of care was not associated with outcomes. Intracranial hemorrhage, GCS 13 to 14, skull fracture, and current antiplatelet/anticoagulant therapy influenced disposition decisions.
doi_str_mv 10.1016/j.ajem.2014.04.003
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Such decisions may contribute to the significant cost of caring for mTBI patients. Understanding the factors that drive disposition decision making and how disposition is associated with outcomes is necessary for developing an evidence-base supporting disposition decisions. We evaluated factors associated with emergency department triage of mTBI patients to 1 of 3 levels of care: home, inpatient floor, or intensive care unit (ICU). Methods This multicenter, prospective, cohort study included patients with isolated head trauma, a cranial computed tomography as part of routine care, and a Glasgow Coma Scale (GCS) score of 13 to 15. Data analysis was performed using multinomial logistic regression. Results Of the 304 patients included, 167 (55%) were discharged home, 76 (25%) were admitted to the inpatient floor, and 61 (20%) were admitted to the ICU. In the multivariable model, admission to the ICU, compared with floor admission, varied by study site, odds ratio (OR) 0.18 (95% confidence interval [CI], 0.06-0.57); antiplatelet/anticoagulation therapy, OR 7.46 (95% CI, 1.79-31.13); skull fracture, OR 7.60 (95% CI, 2.44-23.73); and lower GCS, OR 2.36 (95% CI, 1.05-5.30). No difference in outcome was observed between the 3 levels of care. Conclusion Clinical characteristics and local practice patterns contribute to mTBI disposition decisions. Level of care was not associated with outcomes. Intracranial hemorrhage, GCS 13 to 14, skull fracture, and current antiplatelet/anticoagulant therapy influenced disposition decisions.</description><identifier>ISSN: 0735-6757</identifier><identifier>EISSN: 1532-8171</identifier><identifier>DOI: 10.1016/j.ajem.2014.04.003</identifier><identifier>PMID: 24857248</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Anticoagulants ; Anticoagulants - therapeutic use ; Assaults ; Brain damage ; Brain Injuries - diagnosis ; Brain Injuries - diagnostic imaging ; Brain Injuries - drug therapy ; Brain Injuries - therapy ; Brain research ; Computed tomography ; Consciousness ; Data analysis ; Decision making ; Emergency ; Emergency medical care ; Emergency medical services ; Emergency Service, Hospital - statistics &amp; numerical data ; Female ; Fractures ; Glasgow Coma Scale - statistics &amp; numerical data ; Head injuries ; Hemorrhage ; Hospitalization - statistics &amp; numerical data ; Humans ; Intensive Care Units - statistics &amp; numerical data ; Intracranial Hemorrhage, Traumatic - diagnosis ; Intracranial Hemorrhage, Traumatic - diagnostic imaging ; Intracranial Hemorrhage, Traumatic - therapy ; Logistic Models ; Male ; Neuroimaging ; Neuropsychological Tests ; Patient Outcome Assessment ; Platelet Aggregation Inhibitors - therapeutic use ; Population ; Prospective Studies ; Studies ; Tomography, X-Ray Computed ; Trauma ; Triage - statistics &amp; numerical data ; Variables</subject><ispartof>The American journal of emergency medicine, 2014-08, Vol.32 (8), p.844-850</ispartof><rights>Elsevier Inc.</rights><rights>2014 Elsevier Inc.</rights><rights>Copyright © 2014 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited 2014</rights><rights>2014 Elsevier Inc. All rights reserved. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c608t-634c3aa95b62fe6945981e6331572852899555b508637d978ae36969a9bc2c573</citedby><cites>FETCH-LOGICAL-c608t-634c3aa95b62fe6945981e6331572852899555b508637d978ae36969a9bc2c573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0735675714002435$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24857248$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ratcliff, Jonathan J., MD, MPH</creatorcontrib><creatorcontrib>Adeoye, Opeolu, MD, MS</creatorcontrib><creatorcontrib>Lindsell, Christopher J., PhD</creatorcontrib><creatorcontrib>Hart, Kimberly W., MA</creatorcontrib><creatorcontrib>Pancioli, Arthur, MD</creatorcontrib><creatorcontrib>McMullan, Jason T., MD</creatorcontrib><creatorcontrib>Yue, John K., BS</creatorcontrib><creatorcontrib>Nishijima, Daniel K., MD</creatorcontrib><creatorcontrib>Gordon, Wayne A., PhD</creatorcontrib><creatorcontrib>Valadka, Alex B., MD</creatorcontrib><creatorcontrib>Okonkwo, David O., MD, PhD</creatorcontrib><creatorcontrib>Lingsma, Hester F., PhD</creatorcontrib><creatorcontrib>Maas, Andrew I.R., MD, PhD</creatorcontrib><creatorcontrib>Manley, Geoffrey T., MD PhD</creatorcontrib><creatorcontrib>For the TRACK-TBI investigators</creatorcontrib><creatorcontrib>TRACK-TBI investigators</creatorcontrib><title>ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study</title><title>The American journal of emergency medicine</title><addtitle>Am J Emerg Med</addtitle><description>Abstract Objective Mild traumatic brain injury (mTBI) patients are frequently admitted to high levels of care despite limited evidence suggesting benefit. Such decisions may contribute to the significant cost of caring for mTBI patients. Understanding the factors that drive disposition decision making and how disposition is associated with outcomes is necessary for developing an evidence-base supporting disposition decisions. We evaluated factors associated with emergency department triage of mTBI patients to 1 of 3 levels of care: home, inpatient floor, or intensive care unit (ICU). Methods This multicenter, prospective, cohort study included patients with isolated head trauma, a cranial computed tomography as part of routine care, and a Glasgow Coma Scale (GCS) score of 13 to 15. Data analysis was performed using multinomial logistic regression. Results Of the 304 patients included, 167 (55%) were discharged home, 76 (25%) were admitted to the inpatient floor, and 61 (20%) were admitted to the ICU. In the multivariable model, admission to the ICU, compared with floor admission, varied by study site, odds ratio (OR) 0.18 (95% confidence interval [CI], 0.06-0.57); antiplatelet/anticoagulation therapy, OR 7.46 (95% CI, 1.79-31.13); skull fracture, OR 7.60 (95% CI, 2.44-23.73); and lower GCS, OR 2.36 (95% CI, 1.05-5.30). No difference in outcome was observed between the 3 levels of care. Conclusion Clinical characteristics and local practice patterns contribute to mTBI disposition decisions. Level of care was not associated with outcomes. Intracranial hemorrhage, GCS 13 to 14, skull fracture, and current antiplatelet/anticoagulant therapy influenced disposition decisions.</description><subject>Adult</subject><subject>Anticoagulants</subject><subject>Anticoagulants - therapeutic use</subject><subject>Assaults</subject><subject>Brain damage</subject><subject>Brain Injuries - diagnosis</subject><subject>Brain Injuries - diagnostic imaging</subject><subject>Brain Injuries - drug therapy</subject><subject>Brain Injuries - therapy</subject><subject>Brain research</subject><subject>Computed tomography</subject><subject>Consciousness</subject><subject>Data analysis</subject><subject>Decision making</subject><subject>Emergency</subject><subject>Emergency medical care</subject><subject>Emergency medical services</subject><subject>Emergency Service, Hospital - statistics &amp; numerical data</subject><subject>Female</subject><subject>Fractures</subject><subject>Glasgow Coma Scale - statistics &amp; numerical data</subject><subject>Head injuries</subject><subject>Hemorrhage</subject><subject>Hospitalization - statistics &amp; numerical data</subject><subject>Humans</subject><subject>Intensive Care Units - statistics &amp; numerical data</subject><subject>Intracranial Hemorrhage, Traumatic - diagnosis</subject><subject>Intracranial Hemorrhage, Traumatic - diagnostic imaging</subject><subject>Intracranial Hemorrhage, Traumatic - therapy</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Neuroimaging</subject><subject>Neuropsychological Tests</subject><subject>Patient Outcome Assessment</subject><subject>Platelet Aggregation Inhibitors - therapeutic use</subject><subject>Population</subject><subject>Prospective Studies</subject><subject>Studies</subject><subject>Tomography, X-Ray Computed</subject><subject>Trauma</subject><subject>Triage - statistics &amp; numerical data</subject><subject>Variables</subject><issn>0735-6757</issn><issn>1532-8171</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9Uk1vEzEUtBCIhsAf4IAsceGS4I-114tQJQilVFRCouFsOd6XxMuundq7rfJb-LN4lbRAD8hPtmTPjDxvHkIvKZlTQuXbZm4a6OaM0GJOchH-CE2o4GymaEkfowkpuZjJUpQn6FlKDSGUFqJ4ik5YoUSZtwn6dfYJ1y7tQnK9Cx6HNe63gM9bkzbhFi9CZ_CVNS1gynEfMBW4j2boTO8sXkXjPHa-GeIe7_IV-P4dNt60--TSndYyGp_WIXbOb_B3SGCi3WZUjRet8y6L468-3LZQbyCL4eXHC5z6od4_R0_Wpk3w4nhO0Y_PZ8vFl9nlt_OLxYfLmZVE9TPJC8uNqcRKsjXIqhCVoiA5p9mjEkxVlRBiJYiSvKyrUhngspKVqVaWWVHyKTo96O6GVQe1zS6iafUuus7EvQ7G6X9fvNvqTbjRBVO8rIos8OYoEMP1AKnXnUsW2tZ4CEPSVAhKGKd5TdHrB9AmDDF3bEQVSjFJucgodkDZGFKKsL7_DCV6zF43esxej9lrkovwTHr1t417yl3YGfD-AIDczBsHUSebI7NQuwi213Vw_9c_fUC3x_x-wh7SHx86MU301Th94_DRghBWZFe_AVVQ1GU</recordid><startdate>20140801</startdate><enddate>20140801</enddate><creator>Ratcliff, Jonathan J., MD, MPH</creator><creator>Adeoye, Opeolu, MD, MS</creator><creator>Lindsell, Christopher J., PhD</creator><creator>Hart, Kimberly W., MA</creator><creator>Pancioli, Arthur, MD</creator><creator>McMullan, Jason T., MD</creator><creator>Yue, John K., BS</creator><creator>Nishijima, Daniel K., MD</creator><creator>Gordon, Wayne A., PhD</creator><creator>Valadka, Alex B., MD</creator><creator>Okonkwo, David O., MD, PhD</creator><creator>Lingsma, Hester F., PhD</creator><creator>Maas, Andrew I.R., MD, PhD</creator><creator>Manley, Geoffrey T., MD PhD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140801</creationdate><title>ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study</title><author>Ratcliff, Jonathan J., MD, MPH ; Adeoye, Opeolu, MD, MS ; Lindsell, Christopher J., PhD ; Hart, Kimberly W., MA ; Pancioli, Arthur, MD ; McMullan, Jason T., MD ; Yue, John K., BS ; Nishijima, Daniel K., MD ; Gordon, Wayne A., PhD ; Valadka, Alex B., MD ; Okonkwo, David O., MD, PhD ; Lingsma, Hester F., PhD ; Maas, Andrew I.R., MD, PhD ; Manley, Geoffrey T., MD PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c608t-634c3aa95b62fe6945981e6331572852899555b508637d978ae36969a9bc2c573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Anticoagulants</topic><topic>Anticoagulants - therapeutic use</topic><topic>Assaults</topic><topic>Brain damage</topic><topic>Brain Injuries - diagnosis</topic><topic>Brain Injuries - diagnostic imaging</topic><topic>Brain Injuries - drug therapy</topic><topic>Brain Injuries - therapy</topic><topic>Brain research</topic><topic>Computed tomography</topic><topic>Consciousness</topic><topic>Data analysis</topic><topic>Decision making</topic><topic>Emergency</topic><topic>Emergency medical care</topic><topic>Emergency medical services</topic><topic>Emergency Service, Hospital - statistics &amp; 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Such decisions may contribute to the significant cost of caring for mTBI patients. Understanding the factors that drive disposition decision making and how disposition is associated with outcomes is necessary for developing an evidence-base supporting disposition decisions. We evaluated factors associated with emergency department triage of mTBI patients to 1 of 3 levels of care: home, inpatient floor, or intensive care unit (ICU). Methods This multicenter, prospective, cohort study included patients with isolated head trauma, a cranial computed tomography as part of routine care, and a Glasgow Coma Scale (GCS) score of 13 to 15. Data analysis was performed using multinomial logistic regression. Results Of the 304 patients included, 167 (55%) were discharged home, 76 (25%) were admitted to the inpatient floor, and 61 (20%) were admitted to the ICU. In the multivariable model, admission to the ICU, compared with floor admission, varied by study site, odds ratio (OR) 0.18 (95% confidence interval [CI], 0.06-0.57); antiplatelet/anticoagulation therapy, OR 7.46 (95% CI, 1.79-31.13); skull fracture, OR 7.60 (95% CI, 2.44-23.73); and lower GCS, OR 2.36 (95% CI, 1.05-5.30). No difference in outcome was observed between the 3 levels of care. Conclusion Clinical characteristics and local practice patterns contribute to mTBI disposition decisions. Level of care was not associated with outcomes. Intracranial hemorrhage, GCS 13 to 14, skull fracture, and current antiplatelet/anticoagulant therapy influenced disposition decisions.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>24857248</pmid><doi>10.1016/j.ajem.2014.04.003</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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ispartof The American journal of emergency medicine, 2014-08, Vol.32 (8), p.844-850
issn 0735-6757
1532-8171
language eng
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Adult
Anticoagulants
Anticoagulants - therapeutic use
Assaults
Brain damage
Brain Injuries - diagnosis
Brain Injuries - diagnostic imaging
Brain Injuries - drug therapy
Brain Injuries - therapy
Brain research
Computed tomography
Consciousness
Data analysis
Decision making
Emergency
Emergency medical care
Emergency medical services
Emergency Service, Hospital - statistics & numerical data
Female
Fractures
Glasgow Coma Scale - statistics & numerical data
Head injuries
Hemorrhage
Hospitalization - statistics & numerical data
Humans
Intensive Care Units - statistics & numerical data
Intracranial Hemorrhage, Traumatic - diagnosis
Intracranial Hemorrhage, Traumatic - diagnostic imaging
Intracranial Hemorrhage, Traumatic - therapy
Logistic Models
Male
Neuroimaging
Neuropsychological Tests
Patient Outcome Assessment
Platelet Aggregation Inhibitors - therapeutic use
Population
Prospective Studies
Studies
Tomography, X-Ray Computed
Trauma
Triage - statistics & numerical data
Variables
title ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study
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