Escargot maintains stemness and suppresses differentiation in Drosophila intestinal stem cells

Snail family transcription factors are expressed in various stem cell types, but their function in maintaining stem cell identity is unclear. In the adult Drosophila midgut, the Snail homolog Esg is expressed in intestinal stem cells (ISCs) and their transient undifferentiated daughters, termed ente...

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Veröffentlicht in:	The EMBO journal 2014-12, Vol.33 (24), p.2967-2982
Hauptverfasser:	Korzelius, Jerome, Naumann, Svenja K, Loza-Coll, Mariano A, Chan, Jessica SK, Dutta, Devanjali, Oberheim, Jessica, Gläßer, Christine, Southall, Tony D, Brand, Andrea H, Jones, D Leanne, Edgar, Bruce A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Drosophila - physiology Drosophila midgut Drosophila Proteins - metabolism EMBO11 EMBO39 EMBO44 enterocyte differentiation Gastrointestinal Tract - physiology Gene Deletion Gene Expression Gene Expression Profiling Genes Insects intestinal stem cells Mollusks Pdm1 Snail transcription factors Stem cells Stem Cells - drug effects Stem Cells - physiology Transcription factors
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