Effect of prucalopride on symptoms of chronic constipation

Background Prucalopride is a 5‐HT4 receptor agonist with gastrointestinal prokinetic activities. This integrated analysis of data from three 12‐week, double‐blind trials evaluated the effect of prucalopride 2 mg q.d. on common constipation symptoms in women in whom laxatives had failed to provide ad...

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Veröffentlicht in:	Neurogastroenterology and motility 2014-01, Vol.26 (1), p.21-27
Hauptverfasser:	Tack, J., Stanghellini, V., Dubois, D., Joseph, A., Vandeplassche, L., Kerstens, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	abdominal discomfort Adolescent Adult Aged Aged, 80 and over Benzofurans - therapeutic use bloating chronic constipation Chronic Disease Clinical trials Constipation - diagnosis Constipation - drug therapy Constipation - physiopathology Double-Blind Method Female Humans Laxatives - therapeutic use Middle Aged Original PAC‐SYM painful bowel movements prucalopride Serotonin 5-HT4 Receptor Agonists - therapeutic use Treatment Outcome Young Adult
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