Role of reactive oxygen species in arsenic-induced transformation of human lung bronchial epithelial (BEAS-2B) cells

[Display omitted] •Short term exposure of cells to arsenic causes ROS generation.•Chronical exposure of cells to arsenic causes malignant cell transformation.•Inhibition of ROS generation reduces cell transformation by arsenic.•Arsenic-transformed cells exhibit reduced capacity of generating ROS.•Ar...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2015-01, Vol.456 (2), p.643-648
Hauptverfasser:	Zhang, Zhuo, Pratheeshkumar, Poyil, Budhraja, Amit, Son, Young-Ok, Kim, Donghern, Shi, Xianglin
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Antioxidant enzymes ANTIOXIDANTS APOPTOSIS Apoptosis - drug effects ARSENIC Arsenic - toxicity Bronchi - drug effects Bronchi - metabolism Bronchi - pathology CARCINOGENESIS CARCINOGENS Carcinogens, Environmental - toxicity CATALASE Catalase - antagonists & inhibitors Cell Line CELL PROLIFERATION Cell transformation Cell Transformation, Neoplastic - chemically induced CELL TRANSFORMATIONS EPITHELIUM HUMAN POPULATIONS Humans HYDROGEN PEROXIDE INHIBITION LUNGS OXYGEN Reactive oxygen species Reactive Oxygen Species - metabolism Respiratory Mucosa - drug effects Respiratory Mucosa - metabolism Respiratory Mucosa - pathology SUPEROXIDE DISMUTASE
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!