Bone Regeneration With Osteogenically Enhanced Mesenchymal Stem Cells and Their Extracellular Matrix Proteins

ABSTRACT Although bone has remarkable regenerative capacity, about 10% of long bone fractures and 25% to 40% of vertebral fusion procedures fail to heal. In such instances, a scaffold is employed to bridge the lesion and accommodate osteoprogenitors. Although synthetic bone scaffolds mimic some of t...

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Veröffentlicht in:	Journal of bone and mineral research 2015-01, Vol.30 (1), p.83-94
Hauptverfasser:	Clough, Bret H, McCarley, Matthew R, Krause, Ulf, Zeitouni, Suzanne, Froese, Jeremiah J, McNeill, Eoin P, Chaput, Christopher D, Sampson, H Wayne, Gregory, Carl A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Regeneration Cells, Cultured Cryopreservation EXTRACELLULAR MATRIX Extracellular Matrix - chemistry Extracellular Matrix - metabolism Extracellular Matrix Proteins - biosynthesis FRACTURE HEALING Humans Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism Mice OSTEOGENICALLY ENHANCED MESENCHYMAL STEM CELLS Tissue Scaffolds - chemistry
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