The IL-33/ST2 pathway: therapeutic target and novel biomarker

Key Points Interleukin-33 (IL-33) is a recently discovered member of the IL-1 family of cytokines. The receptor for IL-33, ST2, is present in multiple isoforms, including a membrane-bound form (ST2L), which together with the interleukin-1 (IL-1) receptor accessory protein forms the transmembrane IL-...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature reviews. Drug discovery 2008-10, Vol.7 (10), p.827-840
Hauptverfasser:	Kakkar, Rahul, Lee, Richard T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis - etiology Atherosclerosis - metabolism Biomarkers - metabolism Biomedical and Life Sciences Biomedicine Biotechnology Cancer Research Disease Progression Drug Delivery Systems - methods Drug Delivery Systems - trends Humans Immune response Interleukin-1 Interleukin-1 Receptor-Like 1 Protein Interleukin-18 Interleukin-33 Interleukins - agonists Interleukins - antagonists & inhibitors Interleukins - metabolism Interleukins - physiology Medicinal Chemistry Molecular Medicine Pharmacology/Toxicology Receptors, Cell Surface - agonists Receptors, Cell Surface - antagonists & inhibitors Receptors, Cell Surface - metabolism Receptors, Cell Surface - physiology Regulation review-article Septic shock Signal Transduction - drug effects Signal Transduction - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!