Trichomonas vaginalis Metalloproteinase Induces mTOR Cleavage of SiHa Cells

Trichomonas vaginalis secretes a number of proteases which are suspected to be the cause of pathogenesis; however, little is understood how they manipulate host cells. The mammalian target of rapamycin (mTOR) regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis,...

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Veröffentlicht in:	Korean journal of parasitology 2014, Hosts and Diseases, 52(6), , pp.595-603
Hauptverfasser:	Quan, Juan-Hua, Choi, In-Wook, Yang, Jung-Bo, Zhou, Wei, Cha, Guang-Ho, Zhou, Yu, Ryu, Jae-Sook, Lee, Young-Ha
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Cell Line, Tumor Epithelial Cells - metabolism Epithelial Cells - parasitology Humans Metalloproteases - genetics Metalloproteases - metabolism Original Proteolysis Sequence Analysis, DNA TOR Serine-Threonine Kinases - metabolism Trichomonas vaginalis - enzymology Trichomonas vaginalis - genetics 예방의학
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