Gene Expression of Mesothelioma in Vinylidene Chloride-Exposed F344/N Rats Reveals Immune Dysfunction, Tissue Damage, and Inflammation Pathways

A majority (~80%) of human malignant mesotheliomas are asbestos-related. However, non-asbestos risk factors (radiation, chemicals, genetic factors) account for up to 30% of cases. A recent two-year National Toxicology Program carcinogenicity bioassay showed that male F344/N rats exposed to the indus...

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Veröffentlicht in:	Toxicologic pathology 2014-06, Vol.43 (2), p.171-185
Hauptverfasser:	Blackshear, Pamela E., Pandiri, Arun R., Nagai, Hiroaki, Bhusari, Sachin, Hong, Lily, Ton, Thai-Vu T., Clayton, Natasha P., Wyde, Michael, Shockley, Keith R., Peddada, Shyamal D., Gerrish, Kevin E., Sills, Robert C., Hoenerhoff, Mark J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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