Glial Progenitors as Targets for Transformation in Glioma

Glioma is the most common primary malignant brain tumor and arises throughout the central nervous system. Recent focus on stem-like glioma cells has implicated neural stem cells (NSCs), a minor precursor population restricted to germinal zones, as a potential source of gliomas. In this review, we fo...

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Veröffentlicht in:	Advances in Cancer Research 2014, Vol.121, p.1-65
Hauptverfasser:	Ilkhanizadeh, Shirin, Lau, Jasmine, Huang, Miller, Foster, Daniel J., Wong, Robyn, Frantz, Aaron, Wang, Susan, Weiss, William A., Persson, Anders I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Cancer Cell Differentiation - genetics Cell Lineage - physiology Cell Transformation, Neoplastic - pathology Glioblastoma Glioma Glioma - genetics Glioma - pathology Glioma - therapy Humans Molecular Targeted Therapy Neural stem cell Neural Stem Cells - pathology Neural Stem Cells - physiology Neuroglia - pathology Neuroglia - physiology Oligodendrocyte progenitor cell
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