Defining a mesenchymal progenitor niche at single-cell resolution

Most vertebrate organs are composed of epithelium surrounded by support and stromal tissues formed from mesenchyme cells, which are not generally thought to form organized progenitor pools. Here, we use clonal cell labeling with multicolor reporters to characterize individual mesenchymal progenitors...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2014-11, Vol.346 (6211), p.827-827
Hauptverfasser:	Kumar, Maya E., Bogard, Patrick E., Espinoza, F. Hernán, Menke, Douglas B., Kingsley, David M., Krasnow, Mark A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Airways Animals Boundaries Cellular biology Classical Languages epithelium Individualized Instruction Lungs mice Migration Patterns Movements Muscles niches Organs Pools RESEARCH ARTICLE SUMMARY smooth muscle Stem cells Vertebrates
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