How is water-use efficiency of terrestrial ecosystems distributed and changing on Earth?

A better understanding of ecosystem water-use efficiency (WUE) will help us improve ecosystem management for mitigation as well as adaption to global hydrological change. Here, long-term flux tower observations of productivity and evapotranspiration allow us to detect a consistent latitudinal trend...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Scientific reports 2014-12, Vol.4 (1), p.7483-7483, Article 7483
Hauptverfasser: Tang, Xuguang, Li, Hengpeng, Desai, Ankur R., Nagy, Zoltan, Luo, Juhua, Kolb, Thomas E., Olioso, Albert, Xu, Xibao, Yao, Li, Kutsch, Werner, Pilegaard, Kim, Köstner, Barbara, Ammann, Christof
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 7483
container_issue 1
container_start_page 7483
container_title Scientific reports
container_volume 4
creator Tang, Xuguang
Li, Hengpeng
Desai, Ankur R.
Nagy, Zoltan
Luo, Juhua
Kolb, Thomas E.
Olioso, Albert
Xu, Xibao
Yao, Li
Kutsch, Werner
Pilegaard, Kim
Köstner, Barbara
Ammann, Christof
description A better understanding of ecosystem water-use efficiency (WUE) will help us improve ecosystem management for mitigation as well as adaption to global hydrological change. Here, long-term flux tower observations of productivity and evapotranspiration allow us to detect a consistent latitudinal trend in WUE, rising from the subtropics to the northern high-latitudes. The trend peaks at approximately 51°N and then declines toward higher latitudes. These ground-based observations are consistent with global-scale estimates of WUE. Global analysis of WUE reveals existence of strong regional variations that correspond to global climate patterns. The latitudinal trends of global WUE for Earth's major plant functional types reveal two peaks in the Northern Hemisphere not detected by ground-based measurements. One peak is located at 20° ~ 30°N and the other extends a little farther north than 51°N. Finally, long-term spatiotemporal trend analysis using satellite-based remote sensing data reveals that land-cover and land-use change in recent years has led to a decline in global WUE. Our study provides a new framework for global research on the interactions between carbon and water cycles as well as responses to natural and human impacts.
doi_str_mv 10.1038/srep07483
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4265788</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1639494647</sourcerecordid><originalsourceid>FETCH-LOGICAL-c538t-e0c8816fe9c7781bb6f94440d1709e0192d7c0de61bd9ec4cb14fb1b9f0773d53</originalsourceid><addsrcrecordid>eNplkVFrFDEUhYMottQ--Ack4IsKo7kzmUnyYimlusKCLwq-hUzmZjdlNlmTmZb992bZuqw1Lwnnfjk3uYeQ18A-Amvkp5xwywSXzTNyXjPeVnVT189PzmfkMuc7VlZbKw7qJTmr25YxxeQ5-bWID9Rn-mAmTNWckaJz3noMdkejo0VNmKfkzUjRxrzLE24yHfxe6-cJB2rCQO3ahJUPKxoDvTVpWl-9Ii-cGTNePu4X5OeX2x83i2r5_eu3m-tlZdtGThUyKyV0DpUVQkLfd05xztkAgilkoOpBWDZgB_2g0HLbA3c99MoxIZqhbS7I54Pvdu43OFgMUzKj3ia_MWmno_H630rwa72K95rXXSukLAbvDwbrJ9cW10u91xhAA0yoeyjsu8dmKf6ey1z0xmeL42gCxjlr6BrFFe-4KOjbJ-hdnFMoo9AglQRRojlpblPMJUl3fAEwvY9XH-Mt7JvTnx7Jv2EW4MMByKUUVphOWv7n9gdnEq61</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1898172328</pqid></control><display><type>article</type><title>How is water-use efficiency of terrestrial ecosystems distributed and changing on Earth?</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Springer Nature OA Free Journals</source><source>Nature Free</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Tang, Xuguang ; Li, Hengpeng ; Desai, Ankur R. ; Nagy, Zoltan ; Luo, Juhua ; Kolb, Thomas E. ; Olioso, Albert ; Xu, Xibao ; Yao, Li ; Kutsch, Werner ; Pilegaard, Kim ; Köstner, Barbara ; Ammann, Christof</creator><creatorcontrib>Tang, Xuguang ; Li, Hengpeng ; Desai, Ankur R. ; Nagy, Zoltan ; Luo, Juhua ; Kolb, Thomas E. ; Olioso, Albert ; Xu, Xibao ; Yao, Li ; Kutsch, Werner ; Pilegaard, Kim ; Köstner, Barbara ; Ammann, Christof</creatorcontrib><description>A better understanding of ecosystem water-use efficiency (WUE) will help us improve ecosystem management for mitigation as well as adaption to global hydrological change. Here, long-term flux tower observations of productivity and evapotranspiration allow us to detect a consistent latitudinal trend in WUE, rising from the subtropics to the northern high-latitudes. The trend peaks at approximately 51°N and then declines toward higher latitudes. These ground-based observations are consistent with global-scale estimates of WUE. Global analysis of WUE reveals existence of strong regional variations that correspond to global climate patterns. The latitudinal trends of global WUE for Earth's major plant functional types reveal two peaks in the Northern Hemisphere not detected by ground-based measurements. One peak is located at 20° ~ 30°N and the other extends a little farther north than 51°N. Finally, long-term spatiotemporal trend analysis using satellite-based remote sensing data reveals that land-cover and land-use change in recent years has led to a decline in global WUE. Our study provides a new framework for global research on the interactions between carbon and water cycles as well as responses to natural and human impacts.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/srep07483</identifier><identifier>PMID: 25500908</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/449/2668 ; 704/158/2445 ; 704/445/242 ; Carbon - metabolism ; Carbon cycle ; Climate ; Earth (Planet) ; Ecosystem ; Ecosystem management ; Environmental Sciences ; Evapotranspiration ; Global Changes ; Global climate ; Humanities and Social Sciences ; Humans ; Hydrologic cycle ; Land use ; Latitude ; multidisciplinary ; Remote sensing ; Science ; Terrestrial ecosystems ; Trends ; Water - metabolism ; Water Supply ; Water use</subject><ispartof>Scientific reports, 2014-12, Vol.4 (1), p.7483-7483, Article 7483</ispartof><rights>The Author(s) 2014</rights><rights>Copyright Nature Publishing Group Dec 2014</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><rights>Copyright © 2014, Macmillan Publishers Limited. All rights reserved 2014 Macmillan Publishers Limited. All rights reserved</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c538t-e0c8816fe9c7781bb6f94440d1709e0192d7c0de61bd9ec4cb14fb1b9f0773d53</citedby><cites>FETCH-LOGICAL-c538t-e0c8816fe9c7781bb6f94440d1709e0192d7c0de61bd9ec4cb14fb1b9f0773d53</cites><orcidid>0000-0002-0992-7123 ; 0000-0001-8342-9272</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265788/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265788/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,41120,42189,51576,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25500908$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-01131079$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Tang, Xuguang</creatorcontrib><creatorcontrib>Li, Hengpeng</creatorcontrib><creatorcontrib>Desai, Ankur R.</creatorcontrib><creatorcontrib>Nagy, Zoltan</creatorcontrib><creatorcontrib>Luo, Juhua</creatorcontrib><creatorcontrib>Kolb, Thomas E.</creatorcontrib><creatorcontrib>Olioso, Albert</creatorcontrib><creatorcontrib>Xu, Xibao</creatorcontrib><creatorcontrib>Yao, Li</creatorcontrib><creatorcontrib>Kutsch, Werner</creatorcontrib><creatorcontrib>Pilegaard, Kim</creatorcontrib><creatorcontrib>Köstner, Barbara</creatorcontrib><creatorcontrib>Ammann, Christof</creatorcontrib><title>How is water-use efficiency of terrestrial ecosystems distributed and changing on Earth?</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>A better understanding of ecosystem water-use efficiency (WUE) will help us improve ecosystem management for mitigation as well as adaption to global hydrological change. Here, long-term flux tower observations of productivity and evapotranspiration allow us to detect a consistent latitudinal trend in WUE, rising from the subtropics to the northern high-latitudes. The trend peaks at approximately 51°N and then declines toward higher latitudes. These ground-based observations are consistent with global-scale estimates of WUE. Global analysis of WUE reveals existence of strong regional variations that correspond to global climate patterns. The latitudinal trends of global WUE for Earth's major plant functional types reveal two peaks in the Northern Hemisphere not detected by ground-based measurements. One peak is located at 20° ~ 30°N and the other extends a little farther north than 51°N. Finally, long-term spatiotemporal trend analysis using satellite-based remote sensing data reveals that land-cover and land-use change in recent years has led to a decline in global WUE. Our study provides a new framework for global research on the interactions between carbon and water cycles as well as responses to natural and human impacts.</description><subject>631/449/2668</subject><subject>704/158/2445</subject><subject>704/445/242</subject><subject>Carbon - metabolism</subject><subject>Carbon cycle</subject><subject>Climate</subject><subject>Earth (Planet)</subject><subject>Ecosystem</subject><subject>Ecosystem management</subject><subject>Environmental Sciences</subject><subject>Evapotranspiration</subject><subject>Global Changes</subject><subject>Global climate</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Hydrologic cycle</subject><subject>Land use</subject><subject>Latitude</subject><subject>multidisciplinary</subject><subject>Remote sensing</subject><subject>Science</subject><subject>Terrestrial ecosystems</subject><subject>Trends</subject><subject>Water - metabolism</subject><subject>Water Supply</subject><subject>Water use</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNplkVFrFDEUhYMottQ--Ack4IsKo7kzmUnyYimlusKCLwq-hUzmZjdlNlmTmZb992bZuqw1Lwnnfjk3uYeQ18A-Amvkp5xwywSXzTNyXjPeVnVT189PzmfkMuc7VlZbKw7qJTmr25YxxeQ5-bWID9Rn-mAmTNWckaJz3noMdkejo0VNmKfkzUjRxrzLE24yHfxe6-cJB2rCQO3ahJUPKxoDvTVpWl-9Ii-cGTNePu4X5OeX2x83i2r5_eu3m-tlZdtGThUyKyV0DpUVQkLfd05xztkAgilkoOpBWDZgB_2g0HLbA3c99MoxIZqhbS7I54Pvdu43OFgMUzKj3ia_MWmno_H630rwa72K95rXXSukLAbvDwbrJ9cW10u91xhAA0yoeyjsu8dmKf6ey1z0xmeL42gCxjlr6BrFFe-4KOjbJ-hdnFMoo9AglQRRojlpblPMJUl3fAEwvY9XH-Mt7JvTnx7Jv2EW4MMByKUUVphOWv7n9gdnEq61</recordid><startdate>20141215</startdate><enddate>20141215</enddate><creator>Tang, Xuguang</creator><creator>Li, Hengpeng</creator><creator>Desai, Ankur R.</creator><creator>Nagy, Zoltan</creator><creator>Luo, Juhua</creator><creator>Kolb, Thomas E.</creator><creator>Olioso, Albert</creator><creator>Xu, Xibao</creator><creator>Yao, Li</creator><creator>Kutsch, Werner</creator><creator>Pilegaard, Kim</creator><creator>Köstner, Barbara</creator><creator>Ammann, Christof</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-0992-7123</orcidid><orcidid>https://orcid.org/0000-0001-8342-9272</orcidid></search><sort><creationdate>20141215</creationdate><title>How is water-use efficiency of terrestrial ecosystems distributed and changing on Earth?</title><author>Tang, Xuguang ; Li, Hengpeng ; Desai, Ankur R. ; Nagy, Zoltan ; Luo, Juhua ; Kolb, Thomas E. ; Olioso, Albert ; Xu, Xibao ; Yao, Li ; Kutsch, Werner ; Pilegaard, Kim ; Köstner, Barbara ; Ammann, Christof</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c538t-e0c8816fe9c7781bb6f94440d1709e0192d7c0de61bd9ec4cb14fb1b9f0773d53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>631/449/2668</topic><topic>704/158/2445</topic><topic>704/445/242</topic><topic>Carbon - metabolism</topic><topic>Carbon cycle</topic><topic>Climate</topic><topic>Earth (Planet)</topic><topic>Ecosystem</topic><topic>Ecosystem management</topic><topic>Environmental Sciences</topic><topic>Evapotranspiration</topic><topic>Global Changes</topic><topic>Global climate</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Hydrologic cycle</topic><topic>Land use</topic><topic>Latitude</topic><topic>multidisciplinary</topic><topic>Remote sensing</topic><topic>Science</topic><topic>Terrestrial ecosystems</topic><topic>Trends</topic><topic>Water - metabolism</topic><topic>Water Supply</topic><topic>Water use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tang, Xuguang</creatorcontrib><creatorcontrib>Li, Hengpeng</creatorcontrib><creatorcontrib>Desai, Ankur R.</creatorcontrib><creatorcontrib>Nagy, Zoltan</creatorcontrib><creatorcontrib>Luo, Juhua</creatorcontrib><creatorcontrib>Kolb, Thomas E.</creatorcontrib><creatorcontrib>Olioso, Albert</creatorcontrib><creatorcontrib>Xu, Xibao</creatorcontrib><creatorcontrib>Yao, Li</creatorcontrib><creatorcontrib>Kutsch, Werner</creatorcontrib><creatorcontrib>Pilegaard, Kim</creatorcontrib><creatorcontrib>Köstner, Barbara</creatorcontrib><creatorcontrib>Ammann, Christof</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tang, Xuguang</au><au>Li, Hengpeng</au><au>Desai, Ankur R.</au><au>Nagy, Zoltan</au><au>Luo, Juhua</au><au>Kolb, Thomas E.</au><au>Olioso, Albert</au><au>Xu, Xibao</au><au>Yao, Li</au><au>Kutsch, Werner</au><au>Pilegaard, Kim</au><au>Köstner, Barbara</au><au>Ammann, Christof</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How is water-use efficiency of terrestrial ecosystems distributed and changing on Earth?</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2014-12-15</date><risdate>2014</risdate><volume>4</volume><issue>1</issue><spage>7483</spage><epage>7483</epage><pages>7483-7483</pages><artnum>7483</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>A better understanding of ecosystem water-use efficiency (WUE) will help us improve ecosystem management for mitigation as well as adaption to global hydrological change. Here, long-term flux tower observations of productivity and evapotranspiration allow us to detect a consistent latitudinal trend in WUE, rising from the subtropics to the northern high-latitudes. The trend peaks at approximately 51°N and then declines toward higher latitudes. These ground-based observations are consistent with global-scale estimates of WUE. Global analysis of WUE reveals existence of strong regional variations that correspond to global climate patterns. The latitudinal trends of global WUE for Earth's major plant functional types reveal two peaks in the Northern Hemisphere not detected by ground-based measurements. One peak is located at 20° ~ 30°N and the other extends a little farther north than 51°N. Finally, long-term spatiotemporal trend analysis using satellite-based remote sensing data reveals that land-cover and land-use change in recent years has led to a decline in global WUE. Our study provides a new framework for global research on the interactions between carbon and water cycles as well as responses to natural and human impacts.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>25500908</pmid><doi>10.1038/srep07483</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-0992-7123</orcidid><orcidid>https://orcid.org/0000-0001-8342-9272</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2045-2322
ispartof Scientific reports, 2014-12, Vol.4 (1), p.7483-7483, Article 7483
issn 2045-2322
2045-2322
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4265788
source MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Springer Nature OA Free Journals; Nature Free; PubMed Central; Free Full-Text Journals in Chemistry
subjects 631/449/2668
704/158/2445
704/445/242
Carbon - metabolism
Carbon cycle
Climate
Earth (Planet)
Ecosystem
Ecosystem management
Environmental Sciences
Evapotranspiration
Global Changes
Global climate
Humanities and Social Sciences
Humans
Hydrologic cycle
Land use
Latitude
multidisciplinary
Remote sensing
Science
Terrestrial ecosystems
Trends
Water - metabolism
Water Supply
Water use
title How is water-use efficiency of terrestrial ecosystems distributed and changing on Earth?
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T18%3A43%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=How%20is%20water-use%20efficiency%20of%20terrestrial%20ecosystems%20distributed%20and%20changing%20on%20Earth?&rft.jtitle=Scientific%20reports&rft.au=Tang,%20Xuguang&rft.date=2014-12-15&rft.volume=4&rft.issue=1&rft.spage=7483&rft.epage=7483&rft.pages=7483-7483&rft.artnum=7483&rft.issn=2045-2322&rft.eissn=2045-2322&rft_id=info:doi/10.1038/srep07483&rft_dat=%3Cproquest_pubme%3E1639494647%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1898172328&rft_id=info:pmid/25500908&rfr_iscdi=true