Protein O-GlcNAcylation and Cardiovascular (Patho)physiology

Our understanding of the role of protein O-GlcNAcylation in the regulation of the cardiovascular system has increased rapidly in recent years. Studies have linked increased O-GlcNAc levels to glucose toxicity and diabetic complications; conversely, acute activation of O-GlcNAcylation has been shown...

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Veröffentlicht in:	The Journal of biological chemistry 2014-12, Vol.289 (50), p.34449-34456
Hauptverfasser:	Marsh, Susan A., Collins, Helen E., Chatham, John C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylglucosamine - metabolism Animals Calcium Calcium Signaling Cardiac Hypertrophy Cardiovascular Cardiovascular System - cytology Cardiovascular System - metabolism Cardiovascular System - pathology Cardiovascular System - physiopathology Epigenesis, Genetic Epigenetics Glycosylation Humans Minireviews O-Linked N-Acetylglucosamine (O-GlcNAc) Proteins - genetics Proteins - metabolism
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