Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage‐specific trends in mycolic acid biosynthesis

Mycolic acids (MAs) are α‐alkyl, β‐hydroxy long‐chain fatty acids found in abundance in the cell envelope of the Mycobacterium tuberculosis complex (MTBC). MAs form an efficient permeability barrier, modulate host innate immune responses, and are the targets of several anti‐tuberculosis drugs. Using...

Ausführliche Beschreibung