Temporal dynamics of the ABC transporter response to insecticide treatment: insights from the malaria vector Anopheles stephensi

In insects, ABC transporters have been shown to contribute to defence/resistance to insecticides by reducing toxic concentrations in cells/tissues. Despite the extensive studies about this detoxifying mechanism, the temporal patterns of ABC transporter activation have been poorly investigated. Using...

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Veröffentlicht in:	Scientific reports 2014-12, Vol.4 (1), p.7435, Article 7435
Hauptverfasser:	Epis, Sara, Porretta, Daniele, Mastrantonio, Valentina, Urbanelli, Sandra, Sassera, Davide, De Marco, Leone, Mereghetti, Valeria, Montagna, Matteo, Ricci, Irene, Favia, Guido, Bandi, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	38 38/39 38/77 38/90 631/158/2464 704/158/2452 ABC transporter ABC transporters Amino Acid Sequence Animals Anopheles - drug effects Anopheles - genetics Anopheles - metabolism ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Female Gene expression Gene Expression - drug effects Gene Expression Regulation - drug effects Humanities and Social Sciences Insect Proteins - genetics Insect Proteins - metabolism Insect Vectors - drug effects Insect Vectors - genetics Insect Vectors - metabolism Insecticides Insecticides - pharmacology Investigations Larva - drug effects Larva - genetics Larva - metabolism Larvae Malaria Molecular Sequence Data multidisciplinary Permethrin Permethrin - pharmacology Science Sequence Homology, Amino Acid Vector-borne diseases
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