Cardiomyocyte-Specific BMAL1 Plays Critical Roles in Metabolism, Signaling, and Maintenance of Contractile Function of the Heart

Circadian clocks are cell autonomous, transcriptionally based, molecular mechanisms that confer the selective advantage of anticipation, enabling cells/organs to respond to environmental factors in a temporally appropriate manner. Critical to circadian clock function are 2 transcription factors, CLO...

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Veröffentlicht in:	Journal of biological rhythms 2014-08, Vol.29 (4), p.257-276
Hauptverfasser:	Young, Martin E., Brewer, Rachel A., Peliciari-Garcia, Rodrigo A., Collins, Helen E., He, Lan, Birky, Tana L., Peden, Bradley W., Thompson, Emily G., Ammons, Billy-Joe, Bray, Molly S., Chatham, John C., Wende, Adam R., Yang, Qinglin, Chow, Chi-Wing, Martino, Tami A., Gamble, Karen L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ARNTL Transcription Factors - metabolism Circadian Clocks - physiology Circadian rhythm Circadian Rhythm - physiology Genes Glucose - metabolism Heart Heart - physiology Ketone Bodies - metabolism Male Metabolism Mice Mice, Inbred C57BL Mice, Knockout Myocytes, Cardiac - metabolism Pathology Signal Transduction - physiology
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