Casting inorganic structures with DNA molds
We report a general strategy for designing and synthesizing inorganic nanostructures with arbitrarily prescribed three-dimensional shapes. Computationally designed DNA strands self-assemble into a stiff "nanomold" that contains a user-specified three-dimensional cavity and encloses a nucle...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 2014-11, Vol.346 (6210), p.717-717 |
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| container_title | Science (American Association for the Advancement of Science) |
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| creator | Sun, Wei Boulais, Etienne Hakobyan, Yera Li Wang, Wei Guan, Amy Bathe, Mark Yin, Peng |
| description | We report a general strategy for designing and synthesizing inorganic nanostructures with arbitrarily prescribed three-dimensional shapes. Computationally designed DNA strands self-assemble into a stiff "nanomold" that contains a user-specified three-dimensional cavity and encloses a nucleating gold "seed." Under mild conditions, this seed grows into a larger cast structure that fills and thus replicates the cavity. We synthesized a variety of nanoparticles with 3-nanometer resolution: three distinct silver cuboids with three independently tunable dimensions, silver and gold nanoparticles with diverse cross sections, and composite structures with homo- and heterogeneous components. The designer equilateral silver triangular and spherical nanoparticles exhibited plasmonic properties consistent with electromagnetism-based simulations. Our framework is generalizable to more complex geometries and diverse inorganic materials, offering a range of applications in biosensing, photonics, and nanoelectronics. |
| doi_str_mv | 10.1126/science.1258361 |
| format | Article |
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Computationally designed DNA strands self-assemble into a stiff "nanomold" that contains a user-specified three-dimensional cavity and encloses a nucleating gold "seed." Under mild conditions, this seed grows into a larger cast structure that fills and thus replicates the cavity. We synthesized a variety of nanoparticles with 3-nanometer resolution: three distinct silver cuboids with three independently tunable dimensions, silver and gold nanoparticles with diverse cross sections, and composite structures with homo- and heterogeneous components. The designer equilateral silver triangular and spherical nanoparticles exhibited plasmonic properties consistent with electromagnetism-based simulations. 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Our framework is generalizable to more complex geometries and diverse inorganic materials, offering a range of applications in biosensing, photonics, and nanoelectronics.</description><subject>BASIC BIOLOGICAL SCIENCES</subject><subject>Crystallography</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA - chemistry</subject><subject>Gold</subject><subject>Gold - chemistry</subject><subject>Materials science</subject><subject>Metal Nanoparticles - chemistry</subject><subject>Molds</subject><subject>Molecular Conformation</subject><subject>Nanoparticles</subject><subject>Nanostructure</subject><subject>Nanostructured materials</subject><subject>Nanotechnology - methods</subject><subject>Plasmonics</subject><subject>RESEARCH ARTICLE SUMMARY</subject><subject>Seeds</subject><subject>silver</subject><subject>Silver - chemistry</subject><subject>Strands</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkkuPFCEUhYnROO3o2pWm4mxMTM1weVWxMZm0z2SiG10ToKCbTjWMQGn894PpdnxsZsXifJwL5x6EngI-ByDiotjgonXnQPhIBdxDK8CS95Jgeh-tMKaiH_HAT9CjUnYYN03Sh-iEcIpBDnSFXq11qSFuuhBT3ugYbFdqXmxdsivdj1C33ZtPl90-zVN5jB54PRf35Hieoq_v3n5Zf-ivPr__uL686i0XsvbCMCu8wIAF1QMzxFBG_WQHo5merCd2Ms4b7jSRXk8UvCFaMCK1E6Pxhp6i1wff68Xs3WRdrFnP6jqHvc4_VdJB_avEsFWb9F0xIjARvBm8OBik9jfVMqrObm2K0dmqgDImiWzQy-OUnL4trlS1D8W6edbRpaUo0uKio-AD3ImCxIwQRundrjCCBMoHhht69h-6S0uOLVkFggDB7QVDoy4OlM2plOz8bQ6A1a8OqGMH1LED7cbzv-O75X8vvQHPDsCu1JT_6EzCMIyc3gCJl7bx</recordid><startdate>20141107</startdate><enddate>20141107</enddate><creator>Sun, Wei</creator><creator>Boulais, Etienne</creator><creator>Hakobyan, Yera</creator><creator>Li Wang, Wei</creator><creator>Guan, Amy</creator><creator>Bathe, Mark</creator><creator>Yin, Peng</creator><general>American Association for the Advancement of Science</general><general>The American Association for the Advancement of Science</general><general>AAAS</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QQ</scope><scope>7QR</scope><scope>7SC</scope><scope>7SE</scope><scope>7SN</scope><scope>7SP</scope><scope>7SR</scope><scope>7SS</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7TK</scope><scope>7TM</scope><scope>7U5</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7S9</scope><scope>L.6</scope><scope>OIOZB</scope><scope>OTOTI</scope><scope>5PM</scope></search><sort><creationdate>20141107</creationdate><title>Casting inorganic structures with DNA molds</title><author>Sun, Wei ; Boulais, Etienne ; Hakobyan, Yera ; Li Wang, Wei ; Guan, Amy ; Bathe, Mark ; Yin, Peng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c569t-6b4c6f601063a74b2b343fdc7ba4adcf2cdbefb5ea29fad31fb2a6429ae68bfb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>BASIC BIOLOGICAL SCIENCES</topic><topic>Crystallography</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA - 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Computationally designed DNA strands self-assemble into a stiff "nanomold" that contains a user-specified three-dimensional cavity and encloses a nucleating gold "seed." Under mild conditions, this seed grows into a larger cast structure that fills and thus replicates the cavity. We synthesized a variety of nanoparticles with 3-nanometer resolution: three distinct silver cuboids with three independently tunable dimensions, silver and gold nanoparticles with diverse cross sections, and composite structures with homo- and heterogeneous components. The designer equilateral silver triangular and spherical nanoparticles exhibited plasmonic properties consistent with electromagnetism-based simulations. Our framework is generalizable to more complex geometries and diverse inorganic materials, offering a range of applications in biosensing, photonics, and nanoelectronics.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>25301973</pmid><doi>10.1126/science.1258361</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 2014-11, Vol.346 (6210), p.717-717 |
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| source | American Association for the Advancement of Science; Jstor Complete Legacy; MEDLINE |
| subjects | BASIC BIOLOGICAL SCIENCES Crystallography Deoxyribonucleic acid DNA DNA - chemistry Gold Gold - chemistry Materials science Metal Nanoparticles - chemistry Molds Molecular Conformation Nanoparticles Nanostructure Nanostructured materials Nanotechnology - methods Plasmonics RESEARCH ARTICLE SUMMARY Seeds silver Silver - chemistry Strands |
| title | Casting inorganic structures with DNA molds |
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