The RSC Complex Localizes to Coding Sequences to Regulate Pol II and Histone Occupancy

ATP-dependent chromatin remodelers regulate chromatin structure during multiple stages of transcription. We report that RSC, an essential chromatin remodeler, is recruited to the open reading frames (ORFs) of actively transcribed genes genome wide, suggesting a role for RSC in regulating transcripti...

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Veröffentlicht in:	Molecular cell 2014-12, Vol.56 (5), p.653-666
Hauptverfasser:	Spain, Marla M., Ansari, Suraiya A., Pathak, Rakesh, Palumbo, Michael J., Morse, Randall H., Govind, Chhabi K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatin Assembly and Disassembly DNA-Binding Proteins - metabolism Gene Expression Regulation, Fungal Histones - metabolism Open Reading Frames RNA Polymerase II - metabolism Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Stress, Physiological Transcription Factors - metabolism Transcription, Genetic
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