Exposure to inflammatory cytokines selectively limits GM‐CSF production by induced T regulatory cells

Interest in manipulating the immunosuppressive powers of Foxp3‐expressing T regulatory cells as an immunotherapy has been tempered by their reported ability to produce proinflammatory cytokines when manipulated in vitro, or in vivo. Understanding processes that can limit this potentially deleterious...

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Veröffentlicht in:European journal of immunology 2014-11, Vol.44 (11), p.3342-3352
Hauptverfasser: Reynolds, Ben C., Turner, Darryl G., McPherson, Rhoanne C., Prendergast, Catriona T., Phelps, Richard G., Turner, Neil A., O'Connor, Richard A., Anderton, Stephen M.
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Sprache:eng
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