Quantitative correlation between transcriptional levels of ER chaperone, peroximal protein and FVIII productivity in human Hek-293 cell line

Hek-293 cell line presents good production platform for recombinant therapeutic proteins, however little is known about the components that contribute to the cellular control of recombinant protein production. In this study, we generated a Hek-293 producing recombinant factor VIII (FVIII) and we eva...

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Veröffentlicht in:	SpringerPlus 2013-07, Vol.2 (1), p.328-328, Article 328
Hauptverfasser:	Rodrigues, Evandra Strazza, Picanço-Castro, Virgínia, Espanhol, Marta Regina, de Andrade, Luiz Alberto Martins, Palma, Patricia Vianna Bonini, Kashima, Simone, Fontes, Aparecida Maria, Covas, Dimas Tadeu
Format:	Artikel
Sprache:	eng
Schlagworte:	Humanities and Social Sciences Microbiology and Biotechnology multidisciplinary Science Science (multidisciplinary)
Online-Zugang:	Volltext
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