mRNA-Binding Protein TIA-1 Reduces Cytokine Expression in Human Endometrial Stromal Cells and Is Down-Regulated in Ectopic Endometrium

Background: Cytokines and growth factors play important roles in endometrial function and the pathogenesis of endometriosis. mRNAs encoding cytokines and growth factors undergo rapid turnover; primarily mediated by adenosine- and uridine-rich elements (AREs) located in their 3′-untranslated regions....

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2014-12, Vol.99 (12), p.E2610-E2619
Hauptverfasser:	Karalok, Hakan Mete, Aydin, Ebru, Saglam, Ozlen, Torun, Aysenur, Guzeloglu-Kayisli, Ozlem, Lalioti, Maria D, Kristiansson, Helena, Duke, Cindy M. P, Choe, Gina, Flannery, Clare, Kallen, Caleb B, Seli, Emre
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cell Separation Cells, Cultured Cytokines - biosynthesis Down-Regulation Endometriosis - metabolism Endometrium - cytology Endometrium - drug effects Endometrium - metabolism Estrogens - pharmacology Female Gene Expression - drug effects Gene Expression - physiology Genetic Vectors Hot Topics in Translational Endocrinology Humans Menstrual Cycle - metabolism Poly(A)-Binding Proteins - biosynthesis Poly(A)-Binding Proteins - pharmacology Progesterone - pharmacology Stromal Cells - drug effects Stromal Cells - metabolism T-Cell Intracellular Antigen-1
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