ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect

Non-proliferating cells generate the bulk of cellular ATP by fully oxidizing respiratory substrates in mitochondria. Respiratory substrates cross the mitochondrial outer membrane through only one channel, the voltage dependent anion channel (VDAC). Once in the matrix, respiratory substrates are oxid...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Mitochondrion 2014-11, Vol.19 Pt A, p.78-84
Hauptverfasser:	Maldonado, Eduardo N, Lemasters, John J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - metabolism Adenosine Triphosphate - metabolism Animals Energy Metabolism - physiology Mitochondria - physiology Neoplasms - metabolism Oxygen Consumption - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!